Cytokinesis mechanics and mechanosensing

Hoku West-Foyle, Douglas Robinson

Research output: Contribution to journalArticle

Abstract

Cytokinesis shape change occurs through the interfacing of three modules, cell mechanics, myosin II-mediated contractile stress generation and sensing, and a control system of regulatory proteins, which together ensure flexibility and robustness. This integrated system then defines the stereotypical shape changes of successful cytokinesis, which occurs under a diversity of mechanical contexts and environmental conditions.

Original languageEnglish (US)
Pages (from-to)700-709
Number of pages10
JournalCytoskeleton
Volume69
Issue number10
DOIs
Publication statusPublished - Oct 2012

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Keywords

  • Actin network
  • Contractility
  • Control system
  • Feedback
  • Mechanosensing
  • Myosin II

ASJC Scopus subject areas

  • Cell Biology
  • Structural Biology

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