Cytokines and mycoses

D. A. Stevens, T. J. Walsh, F. Bistoni, E. Cenci, K. V. Clemons, G. Del Sero, C. F È D'Ostiani, B. J. Kullberg, A. Mencacci, E. Roilides, L. Romani

Research output: Contribution to journalArticle

Abstract

Cell-mediated immunity (CMI) has been shown, over many decades of clinical observation and bench research, to be central to the outcome of invasive fungal infections. In recent years, understanding the role of messenger molecules (cytokines), in coordinating and augmenting cellular immunity has been ascendant. These studies have made it possible to consider using cytokines, now available in abundant quantities via recombinant DNA technologies, to treat fungal infections. In this symposium, the most important fungal pathogens that cause infections in humans, particularly in immunocompromised patients, are considered, with emphasis on how recent experimental work may lead to a better understanding of the role of cytokines and their use in therapy.

Original languageEnglish (US)
Pages (from-to)174-182
Number of pages9
JournalJournal of Medical and Veterinary Mycology
Volume3
StatePublished - 1998
Externally publishedYes

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Keywords

  • Cell-mediated immunity
  • Cytokines
  • Immunology
  • Immunotherapy
  • Mycoses

ASJC Scopus subject areas

  • Microbiology

Cite this

Stevens, D. A., Walsh, T. J., Bistoni, F., Cenci, E., Clemons, K. V., Del Sero, G., D'Ostiani, C. F. È., Kullberg, B. J., Mencacci, A., Roilides, E., & Romani, L. (1998). Cytokines and mycoses. Journal of Medical and Veterinary Mycology, 3, 174-182.