Cystoscopic optical coherence tomography for urinary bladder imaging in vivo

Z. G. Wang, H. Adler, D. Chan, A. Jain, H. K. Xie, Z. L. Wu, Y. T. Pan

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper summarizes the development of new 2D MEMS mirrors and the pertinent modification to improve OCT endoscopic catheter packaging suitable for in vivo imaging diagnosis of bladder cancers. Comparative study of the newly developed endocopic OCT versus the bench-top OCT is presented. Results of in vivo OCT cystoscopy based on a porcine acute inflammation model are presented to compare time-domain OCT and spectral-domain OCT for in vivo imaging. In addition, results of spectral-domain Doppler OCT are presented to image blood flow in the lamina propria of the bladder. The results of our in vivo animal study using the presented OCT endoscope are discussed for potential problems in the future clinical applications.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
DOIs
StatePublished - May 10 2006
EventCoherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine X - San Jose, CA, United States
Duration: Jan 23 2006Jan 25 2006

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume6079
ISSN (Print)0277-786X

Other

OtherCoherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine X
CountryUnited States
CitySan Jose, CA
Period1/23/061/25/06

Keywords

  • Backscattering
  • Bladder tumor
  • Laser scanning cystoscopy
  • MEMS mirror
  • Optical coherence Doppler tomography
  • Optical coherence tomography
  • Optical modeling

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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