Cysticercosis as a major cause of epilepsy in Peru

H. H. Garcia, R. Gilman, G. Herrera, F. Diaz, E. Miranda, R. Gilman, M. Martinez, M. Alvarado, V. C.W. Tsang, J. B. Pilcher

Research output: Contribution to journalArticle

Abstract

In countries where cysticercosis is endemic, the proportion of epilepsy due to cysticercosis is not well documented. To investigate the association between cysticercosis and epilepsy, we used the enzyme-linked immunoelectrotransfer blot (EITB) assay to detect serum antibodies to Taenia solium in 498 consecutive outpatients at a neurology clinic in Lima, Peru. Every patient was classified as epileptic (n = 189) or non-epileptic (n=309) after neurological, and where possible electroencephalographic, examination. A substantially higher proportion of epileptic than non-epileptic patients was seropositive in the EITB (22 [12%] vs 8 [3%], p<0·001). 19% of epileptic patients born outside Lima, 20% of those with late-onset epilepsy, and 29% of patients with both these characteristics were seropositive. Thus, in Peru, cysticercosis is an important aetiological factor for epilepsy.

Original languageEnglish (US)
Pages (from-to)197-200
Number of pages4
JournalThe Lancet
Volume341
Issue number8839
DOIs
StatePublished - Jan 23 1993
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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    Garcia, H. H., Gilman, R., Herrera, G., Diaz, F., Miranda, E., Gilman, R., Martinez, M., Alvarado, M., Tsang, V. C. W., & Pilcher, J. B. (1993). Cysticercosis as a major cause of epilepsy in Peru. The Lancet, 341(8839), 197-200. https://doi.org/10.1016/0140-6736(93)90064-N