Cystic paracervical mass as an unusual sequela of graft-versus-host disease: A case report

Dana R. Gossett, F. J. Montz, Robert E. Bristow

Research output: Contribution to journalArticle

Abstract

BACKGROUND: Bone marrow transplantation is used in the treatment of a variety of malignancies. One common sequela is graft-versus-host disease (GvHD.) CASE: A case of vaginal GvHD in a postmenopausal woman manifested as a 2-cm, cystic, paracervical mass. The patient was followed with consecutive pelvic ultrasounds and pelvic examinations until 27 months after transplantation, when the mass increased in size to 4 × 3 cm. Exploratory laparotomy with total abdominal hysterectomy revealed a 3 × 3-cm phlegmon within the proximal part of the vagina. Presumably, this resulted from vaginal GvHD, causing a midvaginal stricture with obstruction of cervical/uterine effluent. CONCLUSION: An awareness of the gynecologic manifestations of GvHD is critical for clinicians caring for women undergoing bone marrow transplantation.

Original languageEnglish (US)
Pages (from-to)600-602
Number of pages3
JournalJournal of Reproductive Medicine for the Obstetrician and Gynecologist
Volume47
Issue number7
StatePublished - 2002

Fingerprint

Graft vs Host Disease
Bone Marrow Transplantation
Gynecological Examination
Cellulitis
Vagina
Hysterectomy
Laparotomy
Pathologic Constriction
Transplantation
Neoplasms
Therapeutics

Keywords

  • Bone marrow transplantation
  • Graft-versus-host disease
  • Vaginal diseases

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Reproductive Medicine

Cite this

Cystic paracervical mass as an unusual sequela of graft-versus-host disease : A case report. / Gossett, Dana R.; Montz, F. J.; Bristow, Robert E.

In: Journal of Reproductive Medicine for the Obstetrician and Gynecologist, Vol. 47, No. 7, 2002, p. 600-602.

Research output: Contribution to journalArticle

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