Cystic malformations within the posterior fossa are rather common findings in pediatric neuroimaging. They may be divided in two main groups based on their location and size: large extra-cerebellar and small intra-cerebellar cystic malformations. Both groups include various diseases: Dandy–Walker malformation, Blake’s pouch cyst, posterior fossa arachnoid cysts, and mega cisterna magna are extra-cerebellar posterior fossa cystic malformations, while α-dystroglycanopathies, GPR56-related fronto-parietal polymicrogyria, and Poretti–Boltshauser due to LAMA1 mutations are intra-cerebellar posterior fossa cystic malformations. These diseases may be differentiated based on the neuroimaging pattern. Differentiation between the various diseases associated with extra- and intra-cerebellar cystic malformations is important in terms of diagnosis, management, prognosis, and counseling of the affected families.
- Posterior fossa
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging