Cysteinyl-tRNA formation: The last puzzle of aminoacyl-tRNA synthesis

Tong Li, David E. Graham, Constantinos Stathopoulos, Paul J. Haney, Hyun Soo Kim, Ute Vothknecht, Makoto Kitabatake, Kwang Won Hong, Gudmundur Eggertsson, Alan W. Curnow, Winston Lin, Ivana Celic, William Whitman, Dieter Söll

Research output: Contribution to journalArticle

Abstract

With the exception of the methanogenic archaea Methanococcus jannaschii and Methanobacterium thermoautotrophicum ΔH, all organisms surveyed contain orthologs of Escherichia coli cysteinyl-tRNA synthetase (CysRS). The characterization of CysRS-encoding (cysS) genes and the demonstration of their ability to complement an E. coli cysS(ts) mutant reveal that Methanococcus maripaludis and Methanosarcina barkeri, two other methanogenic archaea, possess canonical CysRS proteins. A molecular phylogeny inferred from 40 CysRS sequences indicates that the CysRS of M. maripaludis and Methanosarcina spp. are specific relatives of the CysRS of Pyrococcus spp. and Chlamydia, respectively. This result suggests that the CysRS gene was acquired by lateral gene transfer in at least one euryarchaeotic lineage. Copyright (C) 1999 Federation of European Biochemical Societies.

Original languageEnglish (US)
Pages (from-to)302-306
Number of pages5
JournalFEBS Letters
Volume462
Issue number3
DOIs
StatePublished - Dec 3 1999
Externally publishedYes

Fingerprint

cysteinyl-tRNA synthetase
Transfer RNA
Archaea
Escherichia coli
Pyrococcus
Methanosarcina barkeri
Methanococcus
Methanocaldococcus
Methanosarcina
Methanobacterium
Gene transfer
Horizontal Gene Transfer
Gene encoding
Chlamydia
Phylogeny
Genes

Keywords

  • Aminoacyl-tRNA
  • Cysteinyl-tRNA synthetase

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

Li, T., Graham, D. E., Stathopoulos, C., Haney, P. J., Kim, H. S., Vothknecht, U., ... Söll, D. (1999). Cysteinyl-tRNA formation: The last puzzle of aminoacyl-tRNA synthesis. FEBS Letters, 462(3), 302-306. https://doi.org/10.1016/S0014-5793(99)01550-1

Cysteinyl-tRNA formation : The last puzzle of aminoacyl-tRNA synthesis. / Li, Tong; Graham, David E.; Stathopoulos, Constantinos; Haney, Paul J.; Kim, Hyun Soo; Vothknecht, Ute; Kitabatake, Makoto; Hong, Kwang Won; Eggertsson, Gudmundur; Curnow, Alan W.; Lin, Winston; Celic, Ivana; Whitman, William; Söll, Dieter.

In: FEBS Letters, Vol. 462, No. 3, 03.12.1999, p. 302-306.

Research output: Contribution to journalArticle

Li, T, Graham, DE, Stathopoulos, C, Haney, PJ, Kim, HS, Vothknecht, U, Kitabatake, M, Hong, KW, Eggertsson, G, Curnow, AW, Lin, W, Celic, I, Whitman, W & Söll, D 1999, 'Cysteinyl-tRNA formation: The last puzzle of aminoacyl-tRNA synthesis', FEBS Letters, vol. 462, no. 3, pp. 302-306. https://doi.org/10.1016/S0014-5793(99)01550-1
Li T, Graham DE, Stathopoulos C, Haney PJ, Kim HS, Vothknecht U et al. Cysteinyl-tRNA formation: The last puzzle of aminoacyl-tRNA synthesis. FEBS Letters. 1999 Dec 3;462(3):302-306. https://doi.org/10.1016/S0014-5793(99)01550-1
Li, Tong ; Graham, David E. ; Stathopoulos, Constantinos ; Haney, Paul J. ; Kim, Hyun Soo ; Vothknecht, Ute ; Kitabatake, Makoto ; Hong, Kwang Won ; Eggertsson, Gudmundur ; Curnow, Alan W. ; Lin, Winston ; Celic, Ivana ; Whitman, William ; Söll, Dieter. / Cysteinyl-tRNA formation : The last puzzle of aminoacyl-tRNA synthesis. In: FEBS Letters. 1999 ; Vol. 462, No. 3. pp. 302-306.
@article{425a4363563b45479e7bea50c911f62d,
title = "Cysteinyl-tRNA formation: The last puzzle of aminoacyl-tRNA synthesis",
abstract = "With the exception of the methanogenic archaea Methanococcus jannaschii and Methanobacterium thermoautotrophicum ΔH, all organisms surveyed contain orthologs of Escherichia coli cysteinyl-tRNA synthetase (CysRS). The characterization of CysRS-encoding (cysS) genes and the demonstration of their ability to complement an E. coli cysS(ts) mutant reveal that Methanococcus maripaludis and Methanosarcina barkeri, two other methanogenic archaea, possess canonical CysRS proteins. A molecular phylogeny inferred from 40 CysRS sequences indicates that the CysRS of M. maripaludis and Methanosarcina spp. are specific relatives of the CysRS of Pyrococcus spp. and Chlamydia, respectively. This result suggests that the CysRS gene was acquired by lateral gene transfer in at least one euryarchaeotic lineage. Copyright (C) 1999 Federation of European Biochemical Societies.",
keywords = "Aminoacyl-tRNA, Cysteinyl-tRNA synthetase",
author = "Tong Li and Graham, {David E.} and Constantinos Stathopoulos and Haney, {Paul J.} and Kim, {Hyun Soo} and Ute Vothknecht and Makoto Kitabatake and Hong, {Kwang Won} and Gudmundur Eggertsson and Curnow, {Alan W.} and Winston Lin and Ivana Celic and William Whitman and Dieter S{\"o}ll",
year = "1999",
month = "12",
day = "3",
doi = "10.1016/S0014-5793(99)01550-1",
language = "English (US)",
volume = "462",
pages = "302--306",
journal = "FEBS Letters",
issn = "0014-5793",
publisher = "Elsevier",
number = "3",

}

TY - JOUR

T1 - Cysteinyl-tRNA formation

T2 - The last puzzle of aminoacyl-tRNA synthesis

AU - Li, Tong

AU - Graham, David E.

AU - Stathopoulos, Constantinos

AU - Haney, Paul J.

AU - Kim, Hyun Soo

AU - Vothknecht, Ute

AU - Kitabatake, Makoto

AU - Hong, Kwang Won

AU - Eggertsson, Gudmundur

AU - Curnow, Alan W.

AU - Lin, Winston

AU - Celic, Ivana

AU - Whitman, William

AU - Söll, Dieter

PY - 1999/12/3

Y1 - 1999/12/3

N2 - With the exception of the methanogenic archaea Methanococcus jannaschii and Methanobacterium thermoautotrophicum ΔH, all organisms surveyed contain orthologs of Escherichia coli cysteinyl-tRNA synthetase (CysRS). The characterization of CysRS-encoding (cysS) genes and the demonstration of their ability to complement an E. coli cysS(ts) mutant reveal that Methanococcus maripaludis and Methanosarcina barkeri, two other methanogenic archaea, possess canonical CysRS proteins. A molecular phylogeny inferred from 40 CysRS sequences indicates that the CysRS of M. maripaludis and Methanosarcina spp. are specific relatives of the CysRS of Pyrococcus spp. and Chlamydia, respectively. This result suggests that the CysRS gene was acquired by lateral gene transfer in at least one euryarchaeotic lineage. Copyright (C) 1999 Federation of European Biochemical Societies.

AB - With the exception of the methanogenic archaea Methanococcus jannaschii and Methanobacterium thermoautotrophicum ΔH, all organisms surveyed contain orthologs of Escherichia coli cysteinyl-tRNA synthetase (CysRS). The characterization of CysRS-encoding (cysS) genes and the demonstration of their ability to complement an E. coli cysS(ts) mutant reveal that Methanococcus maripaludis and Methanosarcina barkeri, two other methanogenic archaea, possess canonical CysRS proteins. A molecular phylogeny inferred from 40 CysRS sequences indicates that the CysRS of M. maripaludis and Methanosarcina spp. are specific relatives of the CysRS of Pyrococcus spp. and Chlamydia, respectively. This result suggests that the CysRS gene was acquired by lateral gene transfer in at least one euryarchaeotic lineage. Copyright (C) 1999 Federation of European Biochemical Societies.

KW - Aminoacyl-tRNA

KW - Cysteinyl-tRNA synthetase

UR - http://www.scopus.com/inward/record.url?scp=0032699830&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032699830&partnerID=8YFLogxK

U2 - 10.1016/S0014-5793(99)01550-1

DO - 10.1016/S0014-5793(99)01550-1

M3 - Article

C2 - 10622715

AN - SCOPUS:0032699830

VL - 462

SP - 302

EP - 306

JO - FEBS Letters

JF - FEBS Letters

SN - 0014-5793

IS - 3

ER -