Cyst fluid biomarkers - Diagnosis and prediction of malignancy for cystic lesions of the pancreas

Aadhithya Raman; Anne Marie Lennon

doi:10.1159/000490137

Cyst fluid biomarkers - Diagnosis and prediction of malignancy for cystic lesions of the pancreas

Aadhithya Raman, Anne Marie Lennon

School of Medicine

Research output: Contribution to journal › Review article › peer-review

6 Scopus citations

Abstract

Pancreatic cysts are common, and are identified in 2-13% of individuals undergoing cross-sectional imaging. Intraductal papillary mucinous neoplasms (IPMNs) and mucinous cystic neoplasms (MCNs) are pancreatic cysts which are precursors to pancreatic adenocarcinoma. Currently available tools are imperfect at differentiating IPMNs and MCNs from other, benign types of pancreatic cysts. The role of molecular markers in the evaluation of pancreatic cysts and the identification of cysts with high-grade dysplasia or invasive adenocarcinoma is reviewed.

Original language	English (US)
Pages (from-to)	178-181
Number of pages	4
Journal	Visceral Medicine
Volume	34
Issue number	3
DOIs	https://doi.org/10.1159/000490137
State	Published - Jul 1 2018

Keywords

Biomarkers
Intraductal papillary mucinous neoplasm
Mucinous cystic neoplasm
Pancreatic cysts
Serous cystadenomas

ASJC Scopus subject areas

Surgery
Gastroenterology

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10.1159/000490137

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title = "Cyst fluid biomarkers - Diagnosis and prediction of malignancy for cystic lesions of the pancreas",

abstract = "Pancreatic cysts are common, and are identified in 2-13% of individuals undergoing cross-sectional imaging. Intraductal papillary mucinous neoplasms (IPMNs) and mucinous cystic neoplasms (MCNs) are pancreatic cysts which are precursors to pancreatic adenocarcinoma. Currently available tools are imperfect at differentiating IPMNs and MCNs from other, benign types of pancreatic cysts. The role of molecular markers in the evaluation of pancreatic cysts and the identification of cysts with high-grade dysplasia or invasive adenocarcinoma is reviewed.",

keywords = "Biomarkers, Intraductal papillary mucinous neoplasm, Mucinous cystic neoplasm, Pancreatic cysts, Serous cystadenomas",

author = "Aadhithya Raman and Lennon, {Anne Marie}",

note = "Funding Information: This research was supported by the Lustgarten Foundation for Pancreatic Cancer Research, The Sol Goldman Center for Pancreatic Cancer Research, The Benjamin Baker Scholarship, and National Institutes of Health Grants R01CA176828, P50CA062924. Publisher Copyright: {\textcopyright} 2018 S. Karger GmbH, Freiburg.",

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AU - Raman, Aadhithya

AU - Lennon, Anne Marie

N1 - Funding Information: This research was supported by the Lustgarten Foundation for Pancreatic Cancer Research, The Sol Goldman Center for Pancreatic Cancer Research, The Benjamin Baker Scholarship, and National Institutes of Health Grants R01CA176828, P50CA062924. Publisher Copyright: © 2018 S. Karger GmbH, Freiburg.

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N2 - Pancreatic cysts are common, and are identified in 2-13% of individuals undergoing cross-sectional imaging. Intraductal papillary mucinous neoplasms (IPMNs) and mucinous cystic neoplasms (MCNs) are pancreatic cysts which are precursors to pancreatic adenocarcinoma. Currently available tools are imperfect at differentiating IPMNs and MCNs from other, benign types of pancreatic cysts. The role of molecular markers in the evaluation of pancreatic cysts and the identification of cysts with high-grade dysplasia or invasive adenocarcinoma is reviewed.

AB - Pancreatic cysts are common, and are identified in 2-13% of individuals undergoing cross-sectional imaging. Intraductal papillary mucinous neoplasms (IPMNs) and mucinous cystic neoplasms (MCNs) are pancreatic cysts which are precursors to pancreatic adenocarcinoma. Currently available tools are imperfect at differentiating IPMNs and MCNs from other, benign types of pancreatic cysts. The role of molecular markers in the evaluation of pancreatic cysts and the identification of cysts with high-grade dysplasia or invasive adenocarcinoma is reviewed.

KW - Biomarkers

KW - Intraductal papillary mucinous neoplasm

KW - Mucinous cystic neoplasm

KW - Pancreatic cysts

KW - Serous cystadenomas

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Cyst fluid biomarkers - Diagnosis and prediction of malignancy for cystic lesions of the pancreas

Abstract

Keywords

ASJC Scopus subject areas

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