Cyclooxygenase-1 inhibition reduces amyloid pathology and improves memory deficits in a mouse model of Alzheimer's disease

Medicine & Life Sciences

• Cyclooxygenase 1 69%
• Memory Disorders 56%
• Amyloid 50%
• Psychological Inhibition 43%
• Alzheimer disease, familial, type 3 43%
• Alzheimer Disease 41%
• Pathology 33%
• SC 560 33%
• Amyloid Plaques 14%
• Cyclooxygenase 2 14%
• Microglia 13%
• Spatial Learning 8%
• Cyclooxygenase Inhibitors 8%
• Cyclooxygenase 2 Inhibitors 7%
• Neuropathology 7%
• Spatial Memory 7%
• Interleukins 7%
• Prostaglandin-Endoperoxide Synthases 7%
• Brain Injuries 6%
• Neuroglia 5%
• Lipopolysaccharides 5%
• Epidemiologic Studies 5%
• Disease Progression 5%
• Cognition 5%
• Anti-Inflammatory Agents 4%
• Aptitude 4%
• Clinical Trials 4%
• Phenotype 4%
• Therapeutics 3%
• Brain 3%
• Pharmaceutical Preparations 2%

Chemical Compounds

• Cyclooxygenase 1 Inhibitor 100%
• Cyclooxygenase 2 Inhibitor 80%
• Phagocytic 72%
• Nonsteroid Antiinflammatory Agent 61%
• Lipopolysaccharide 58%
• Marker 46%