Cutaneous T-cell lymphoma - An overview

B. Micaily, L. W. Brady, E. C. Vonderheid

Research output: Contribution to journalArticle

Abstract

Mycosis fungoides and Sezary syndrome are malignant lymphoproliferative disorders of mature T-lymphocytes. The term cutaneous T-cell lymphoma (CTCL) is used to emphasize the most important unifying feature of these diseases, namely, the preferential infiltration of the skin with neoplastic T-lymphocytes. Although the different treatments administered to the skin result in temporary responses, their curative potential needs to be confirmed by long-term follow-up. Combined total skin electron beam therapy and total nodal irradiation is a relatively safe treatment, and early results in patients with disease limited to the skin are encouraging. Available systemic treatments are palliative at best, and there is a need for more effective systemic treatments to alter the natural course of the disease.

Original languageEnglish (US)
Pages (from-to)50-56
Number of pages7
JournalApplied Radiology
Volume16
Issue number10
StatePublished - 1987
Externally publishedYes

Fingerprint

Cutaneous T-Cell Lymphoma
Skin
Sezary Syndrome
T-Lymphocytes
Mycosis Fungoides
Lymphoproliferative Disorders
Therapeutics
Palliative Care
Electrons

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Micaily, B., Brady, L. W., & Vonderheid, E. C. (1987). Cutaneous T-cell lymphoma - An overview. Applied Radiology, 16(10), 50-56.

Cutaneous T-cell lymphoma - An overview. / Micaily, B.; Brady, L. W.; Vonderheid, E. C.

In: Applied Radiology, Vol. 16, No. 10, 1987, p. 50-56.

Research output: Contribution to journalArticle

Micaily, B, Brady, LW & Vonderheid, EC 1987, 'Cutaneous T-cell lymphoma - An overview', Applied Radiology, vol. 16, no. 10, pp. 50-56.
Micaily B, Brady LW, Vonderheid EC. Cutaneous T-cell lymphoma - An overview. Applied Radiology. 1987;16(10):50-56.
Micaily, B. ; Brady, L. W. ; Vonderheid, E. C. / Cutaneous T-cell lymphoma - An overview. In: Applied Radiology. 1987 ; Vol. 16, No. 10. pp. 50-56.
@article{ec2f50d925154d51bb15085e035c7a88,
title = "Cutaneous T-cell lymphoma - An overview",
abstract = "Mycosis fungoides and Sezary syndrome are malignant lymphoproliferative disorders of mature T-lymphocytes. The term cutaneous T-cell lymphoma (CTCL) is used to emphasize the most important unifying feature of these diseases, namely, the preferential infiltration of the skin with neoplastic T-lymphocytes. Although the different treatments administered to the skin result in temporary responses, their curative potential needs to be confirmed by long-term follow-up. Combined total skin electron beam therapy and total nodal irradiation is a relatively safe treatment, and early results in patients with disease limited to the skin are encouraging. Available systemic treatments are palliative at best, and there is a need for more effective systemic treatments to alter the natural course of the disease.",
author = "B. Micaily and Brady, {L. W.} and Vonderheid, {E. C.}",
year = "1987",
language = "English (US)",
volume = "16",
pages = "50--56",
journal = "Applied Radiology",
issn = "0160-9963",
publisher = "Anderson Publishing Ltd",
number = "10",

}

TY - JOUR

T1 - Cutaneous T-cell lymphoma - An overview

AU - Micaily, B.

AU - Brady, L. W.

AU - Vonderheid, E. C.

PY - 1987

Y1 - 1987

N2 - Mycosis fungoides and Sezary syndrome are malignant lymphoproliferative disorders of mature T-lymphocytes. The term cutaneous T-cell lymphoma (CTCL) is used to emphasize the most important unifying feature of these diseases, namely, the preferential infiltration of the skin with neoplastic T-lymphocytes. Although the different treatments administered to the skin result in temporary responses, their curative potential needs to be confirmed by long-term follow-up. Combined total skin electron beam therapy and total nodal irradiation is a relatively safe treatment, and early results in patients with disease limited to the skin are encouraging. Available systemic treatments are palliative at best, and there is a need for more effective systemic treatments to alter the natural course of the disease.

AB - Mycosis fungoides and Sezary syndrome are malignant lymphoproliferative disorders of mature T-lymphocytes. The term cutaneous T-cell lymphoma (CTCL) is used to emphasize the most important unifying feature of these diseases, namely, the preferential infiltration of the skin with neoplastic T-lymphocytes. Although the different treatments administered to the skin result in temporary responses, their curative potential needs to be confirmed by long-term follow-up. Combined total skin electron beam therapy and total nodal irradiation is a relatively safe treatment, and early results in patients with disease limited to the skin are encouraging. Available systemic treatments are palliative at best, and there is a need for more effective systemic treatments to alter the natural course of the disease.

UR - http://www.scopus.com/inward/record.url?scp=0023634430&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023634430&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0023634430

VL - 16

SP - 50

EP - 56

JO - Applied Radiology

JF - Applied Radiology

SN - 0160-9963

IS - 10

ER -