TY - JOUR
T1 - Cutaneous ciliated cyst
T2 - A case report with focus on mullerian heterotopia and comparison with eccrine sweat glands
AU - Bivin, William W.
AU - Heath, Jonathon E.
AU - Drachenberg, Cinthia B.
AU - Strauch, Eric D.
AU - Papadimitriou, John C.
PY - 2010/10/1
Y1 - 2010/10/1
N2 - Cutaneous ciliated cyst is an exceedingly rare, benign lesion most commonly found in the dermis or subcutis of the lower extremities of young female patients in their second and third decades. The pathogenesis of the cyst is unknown. We report a cutaneous ciliated cyst in the lower extremity of a 13-year-old female patient. On histologic examination, clusters of eccrine sweat glands were observed adjacent to the cyst. Upon comparison of the immunohistochemical profile of the cutaneous ciliated cyst and the eccrine sweat glands, they appeared almost completely unrelated. The histologic, immunohistochemical, and ultrastructural findings of this case and the literature provide evidence in favor of the Mullerian heterotopia theory.
AB - Cutaneous ciliated cyst is an exceedingly rare, benign lesion most commonly found in the dermis or subcutis of the lower extremities of young female patients in their second and third decades. The pathogenesis of the cyst is unknown. We report a cutaneous ciliated cyst in the lower extremity of a 13-year-old female patient. On histologic examination, clusters of eccrine sweat glands were observed adjacent to the cyst. Upon comparison of the immunohistochemical profile of the cutaneous ciliated cyst and the eccrine sweat glands, they appeared almost completely unrelated. The histologic, immunohistochemical, and ultrastructural findings of this case and the literature provide evidence in favor of the Mullerian heterotopia theory.
KW - Mullerian heterotopia
KW - ciliated epithelium
KW - cutaneous ciliated cyst
KW - eccrine metaplasia
KW - skin
UR - http://www.scopus.com/inward/record.url?scp=77957338945&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77957338945&partnerID=8YFLogxK
U2 - 10.1097/DAD.0b013e3181d43f01
DO - 10.1097/DAD.0b013e3181d43f01
M3 - Article
C2 - 20644463
AN - SCOPUS:77957338945
SN - 0193-1091
VL - 32
SP - 731
EP - 734
JO - American Journal of Dermatopathology
JF - American Journal of Dermatopathology
IS - 7
ER -