Current Treatment Recommendations for Correcting Vitamin D Deficiency in Pediatric Patients with Cystic Fibrosis Are Inadequate

Deanna Green, Kathryn Anne Carson, Amanda Leonard, J. Erin Davis, Beryl J Rosenstein, Pamela Zeitlin, Peter Mogayzel

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Abstract

Objectives: To determine the prevalence of vitamin D deficiency (25-hydroxy vitamin D [25-OHD] levels in plasma 12 years old were more likely to have deficiency than patients 2 P value = .80, .34, and .22, respectively). Conclusions: The prevalence of vitamin D deficiency is high, but declined with time. Age, forced expiratory volume in 1 second, and season were associated with 25-OHD levels. Despite 33% of patients responding to 50 000 IU of ergocalciferol once a week, this recommendation does not adequately treat most patients with CF who have vitamin D deficiency.

Original languageEnglish (US)
JournalJournal of Pediatrics
Volume153
Issue number4
DOIs
Publication statusPublished - Oct 2008

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ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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