Current status of midinfrared quantum and interband cascade lasers for clinical breath analysis

Terence H Risby, Frank K. Tittel

Research output: Contribution to journalArticle

Abstract

State-of-the-art quantum- and interband-cascade-based chemical sensors may be effective new tools for the identification and quantification of trace gases in human breath for clinical uses. Increased or decreased concentrations of these molecules are associated with the pathogenesis of a large number of diseases. Current technologies enable breath analyses to be performed on a single breath and the results are available in real time. Critical parameters including sensor sensitivity, selectivity, real-time monitoring capability, robustness, cost, size, and weight determine the progress made toward the development and availability of commercial diagnostic material.

Original languageEnglish (US)
Article number111123
JournalOptical Engineering
Volume49
Issue number11
DOIs
StatePublished - Nov 2010

Fingerprint

Chemical sensors
cascades
Availability
pathogenesis
Molecules
Lasers
Monitoring
sensors
Sensors
Gases
lasers
availability
Costs
selectivity
costs
gases
molecules

Keywords

  • breath sampling
  • interband cascade lasers
  • midinfrared semiconductor-laser-based chemical sensor
  • quantum cascade lasers
  • real-time breath analysis
  • single-frequency, tunable external cavity quantum cascadeinterband lasers

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Engineering(all)

Cite this

Current status of midinfrared quantum and interband cascade lasers for clinical breath analysis. / Risby, Terence H; Tittel, Frank K.

In: Optical Engineering, Vol. 49, No. 11, 111123, 11.2010.

Research output: Contribution to journalArticle

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