Current State of Immune-Based Therapies for Glioblastoma

Michael Lim, Michael Weller, E. Antonio Chiocca

Research output: Contribution to journalReview articlepeer-review

Abstract

Glioblastoma is one of the most aggressive solid tumors, and, despite treatment options such as surgery, radiation, and chemotherapy, its prognosis remains grim. Novel approaches are needed to improve survival. Immunotherapy has proven efficacy for melanoma, lung cancer, and kidney cancer and is now a focus for glioblastoma. In this article, glioblastoma-mediated immunosuppression will be discussed and two exciting immune approaches, checkpoint inhibitors and viral-based therapies, will be reviewed.

Original languageEnglish (US)
Pages (from-to)e132-e139
JournalAmerican Society of Clinical Oncology educational book. American Society of Clinical Oncology. Meeting
Volume35
DOIs
StatePublished - 2016

ASJC Scopus subject areas

  • Medicine(all)

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