Current perspectives on giardiasis

C. H. Fisher, Sang Oh Kook Sang Oh, Theodore M Bayless, S. S. Siegelman

Research output: Contribution to journalArticle


Giardia lamblia infestation can cause severe diarrhea and malabsorption, and the diagnosis is usually made by identification of cysts in the feces, but small intestinal biopsy or smears may be required. A wide spectrum of roentgen changes may be seen. In patients with a normal immune status, the small bowel is normal or shows an inflammatory bowel disease pattern. Eradication of the parasite reverses these changes. In some patients with IgA deficiency, nodular lymphoid hyperplasia occurs, and this is usually not reversible. Other patients with hypogammaglobulinemia or dysgammaglobulinemia and giardiasis may show a sprue pattern. This pattern most often persists after eradication of the parasite. Although the triad of giardiasis, IgA deficiency, and nodular lymphoid hyperplasia has a particularly high association, these, together with diarrhea, malabsorption, and various altered immune states may occur in any combination.

Original languageEnglish (US)
Pages (from-to)207-217
Number of pages11
JournalAmerican Journal of Roentgenology
Issue number1
Publication statusPublished - 1975


ASJC Scopus subject areas

  • Medicine(all)

Cite this

Fisher, C. H., Kook Sang Oh, S. O., Bayless, T. M., & Siegelman, S. S. (1975). Current perspectives on giardiasis. American Journal of Roentgenology, 125(1), 207-217.