Abstract
Pancreatic ductal adenocarcinoma is one of the deadliest malignancies with an extremely poor survival rate. Both environmental and hereditary factors play a role in the development of disease, and early diagnosis is difficult due to early systemic involvement of disease. Thus, a majority of patients are not surgical candidates at the time of diagnosis. The treatment of pancreatic cancer is dependent on the stage of disease. Several controversies exist that are relevant to surgery. These include: (1) the use of diagnostic laparoscopy, (2) surgery-first versus neoadjuvant approach, (3) definition of borderline resectable, and (4) ablative therapies for locally unresectable pancreatic cancer. This chapter discusses the current principles of the management related to these topics and their variation across different centers and physicians treating pancreatic cancer.
| Original language | English (US) |
|---|---|
| Title of host publication | Current Controversies in Cancer Care for the Surgeon |
| Publisher | Springer International Publishing |
| Pages | 121-132 |
| Number of pages | 12 |
| ISBN (Print) | 9783319162058, 9783319162041 |
| DOIs | |
| State | Published - Jan 1 2015 |
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Keywords
- Ablation
- Borderline resectable
- Controversies
- Diagnostic laparoscopy
- Management
- Neoadjuvant therapy
- Pancreatectomy
- Pancreatic adenocarcinoma
- Pancreatic cancer
- Resectability
ASJC Scopus subject areas
- Medicine(all)
Cite this
Current controversies in the surgical management of pancreatic cancer. / Javed, Ammar Asrar; Aziz, Kanza; Wolfgang, Christopher.
Current Controversies in Cancer Care for the Surgeon. Springer International Publishing, 2015. p. 121-132.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Current controversies in the surgical management of pancreatic cancer
AU - Javed, Ammar Asrar
AU - Aziz, Kanza
AU - Wolfgang, Christopher
PY - 2015/1/1
Y1 - 2015/1/1
N2 - Pancreatic ductal adenocarcinoma is one of the deadliest malignancies with an extremely poor survival rate. Both environmental and hereditary factors play a role in the development of disease, and early diagnosis is difficult due to early systemic involvement of disease. Thus, a majority of patients are not surgical candidates at the time of diagnosis. The treatment of pancreatic cancer is dependent on the stage of disease. Several controversies exist that are relevant to surgery. These include: (1) the use of diagnostic laparoscopy, (2) surgery-first versus neoadjuvant approach, (3) definition of borderline resectable, and (4) ablative therapies for locally unresectable pancreatic cancer. This chapter discusses the current principles of the management related to these topics and their variation across different centers and physicians treating pancreatic cancer.
AB - Pancreatic ductal adenocarcinoma is one of the deadliest malignancies with an extremely poor survival rate. Both environmental and hereditary factors play a role in the development of disease, and early diagnosis is difficult due to early systemic involvement of disease. Thus, a majority of patients are not surgical candidates at the time of diagnosis. The treatment of pancreatic cancer is dependent on the stage of disease. Several controversies exist that are relevant to surgery. These include: (1) the use of diagnostic laparoscopy, (2) surgery-first versus neoadjuvant approach, (3) definition of borderline resectable, and (4) ablative therapies for locally unresectable pancreatic cancer. This chapter discusses the current principles of the management related to these topics and their variation across different centers and physicians treating pancreatic cancer.
KW - Ablation
KW - Borderline resectable
KW - Controversies
KW - Diagnostic laparoscopy
KW - Management
KW - Neoadjuvant therapy
KW - Pancreatectomy
KW - Pancreatic adenocarcinoma
KW - Pancreatic cancer
KW - Resectability
UR - http://www.scopus.com/inward/record.url?scp=84958891128&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84958891128&partnerID=8YFLogxK
U2 - 10.1007/978-3-319-16205-8_7
DO - 10.1007/978-3-319-16205-8_7
M3 - Chapter
AN - SCOPUS:84958891128
SN - 9783319162058
SN - 9783319162041
SP - 121
EP - 132
BT - Current Controversies in Cancer Care for the Surgeon
PB - Springer International Publishing
ER -