Abstract
Pancreatic ductal adenocarcinoma is one of the deadliest malignancies with an extremely poor survival rate. Both environmental and hereditary factors play a role in the development of disease, and early diagnosis is difficult due to early systemic involvement of disease. Thus, a majority of patients are not surgical candidates at the time of diagnosis. The treatment of pancreatic cancer is dependent on the stage of disease. Several controversies exist that are relevant to surgery. These include: (1) the use of diagnostic laparoscopy, (2) surgery-first versus neoadjuvant approach, (3) definition of borderline resectable, and (4) ablative therapies for locally unresectable pancreatic cancer. This chapter discusses the current principles of the management related to these topics and their variation across different centers and physicians treating pancreatic cancer.
| Original language | English (US) |
|---|---|
| Title of host publication | Current Controversies in Cancer Care for the Surgeon |
| Publisher | Springer International Publishing |
| Pages | 121-132 |
| Number of pages | 12 |
| ISBN (Electronic) | 9783319162058 |
| ISBN (Print) | 9783319162041 |
| DOIs | |
| State | Published - Jan 1 2015 |
Keywords
- Ablation
- Borderline resectable
- Controversies
- Diagnostic laparoscopy
- Management
- Neoadjuvant therapy
- Pancreatectomy
- Pancreatic adenocarcinoma
- Pancreatic cancer
- Resectability
ASJC Scopus subject areas
- Medicine(all)