Current Concepts of Cardiac Amyloidosis: Diagnosis, Clinical Management, and the Need for Collaboration

Alexandra J. Ritts, Robert F. Cornell, Kristopher Swiger, Jai Singh, Stacey Goodman, Daniel J. Lenihan

Research output: Contribution to journalReview articlepeer-review

Abstract

Cardiac amyloidosis is a complex and vexing clinical condition that requires a high degree of suspicion for the diagnosis with a substantial amount of discipline to discern the extent of disease and the best available therapy. There is a complex interplay between multiple organ systems, and the clinical presentation may involve a myriad of confusing clinical symptoms. The diagnosis of cardiac amyloidosis can be confirmed with a combination of physical findings, cardiac biomarkers, noninvasive testing, and, if necessary, myocardial biopsy. Genetic testing is critical to establish the type of amyloidosis.

Original languageEnglish (US)
Pages (from-to)409-416
Number of pages8
JournalHeart Failure Clinics
Volume13
Issue number2
DOIs
StatePublished - Apr 1 2017
Externally publishedYes

Keywords

  • Cardiac amyloidosis
  • Cardiotoxicity
  • Immunomodulatory drugs
  • Multiple myeloma
  • Proteasome inhibitors
  • TTR

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Current Concepts of Cardiac Amyloidosis: Diagnosis, Clinical Management, and the Need for Collaboration'. Together they form a unique fingerprint.

Cite this