Current concepts and techniques in keratoprosthesis

Ozge Ilhan-Sarac, Esen Karamursel Akpek

Research output: Contribution to journalReview articlepeer-review

73 Scopus citations


Purpose of review: Diseases affecting the cornea are a major cause of blindness worldwide, second only to cataract in overall importance, with all estimated 10 to 15 million affected people. Although keratoplasty is by far the most successful transplantation surgery, the outcomes in high-risk adult patients, including those with ocular surface diseases and multiple graft rejections, and in pediatric patients with congenital corneal opacities are disappointing. Recent developments: Regrettably, no significant clinical developments have been achieved in the field of corneal transplantation since the introduction of steroids for graft rejection. Furthermore, obtaining donor corneal tissues and eye banking, particularly in the developing countries where corneal blindness is most prevalent, are problematic. Although the postoperative complications may be severe and limit the use of currently available devices, keratoprosthesis - artificial corneal implantation - has a role in the management of corneal blindness in carefully selected patients with complex ocular diseases who are at high risk for graft failure. Summary: This article reviews the recent ophthalmic literature published on the current concepts and techniques of keratoprosthesis surgery.

Original languageEnglish (US)
Pages (from-to)246-250
Number of pages5
JournalCurrent opinion in ophthalmology
Issue number4
StatePublished - Aug 1 2005


  • Cornea
  • Keratoprosthesis
  • Surgery
  • Techniques
  • Transplantation

ASJC Scopus subject areas

  • Ophthalmology


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