Curative therapy for bladder cancer in routine clinical practice: A population-based outcomes study

C. M. Booth; D. R. Siemens; G. Li; Y. Peng; W. Kong; D. M. Berman; W. J. Mackillop

doi:10.1016/j.clon.2014.05.007

Curative therapy for bladder cancer in routine clinical practice: A population-based outcomes study

C. M. Booth, D. R. Siemens, G. Li, Y. Peng, W. Kong, D. M. Berman, W. J. Mackillop

Research output: Contribution to journal › Article › peer-review

41 Scopus citations

Abstract

Aims: Definitive therapy of bladder cancer involves cystectomy or radiotherapy; controversy exists regarding optimal management. Here we describe the management and outcomes of patients treated in routine practice. Materials and methods: Treatment records were linked to the Ontario Cancer Registry to identify all cases of bladder cancer in Ontario treated with cystectomy or radiotherapy in 1994-2008. Practice patterns are described in three study periods: 1994-1998, 1999-2003, 2004-2008. Logistic regression, Cox model and propensity score analyses were used to evaluate factors associated with treatment choice and survival. Results: In total, 3879 cases (74%) underwent cystectomy and 1380 (26%) were treated with primary radiotherapy. Cystectomy use increased over time (66, 75, 78%), whereas radiotherapy decreased (34, 25, 22%), P

Original language	English (US)
Pages (from-to)	506-514
Number of pages	9
Journal	Clinical Oncology
Volume	26
Issue number	8
DOIs	https://doi.org/10.1016/j.clon.2014.05.007
State	Published - 2014
Externally published	Yes

Keywords

Bladder cancer
Cystectomy
Health services
Outcomes
Quality of care
Radiation

ASJC Scopus subject areas

Oncology
Radiology Nuclear Medicine and imaging
Medicine(all)

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10.1016/j.clon.2014.05.007

Cite this

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abstract = "Aims: Definitive therapy of bladder cancer involves cystectomy or radiotherapy; controversy exists regarding optimal management. Here we describe the management and outcomes of patients treated in routine practice. Materials and methods: Treatment records were linked to the Ontario Cancer Registry to identify all cases of bladder cancer in Ontario treated with cystectomy or radiotherapy in 1994-2008. Practice patterns are described in three study periods: 1994-1998, 1999-2003, 2004-2008. Logistic regression, Cox model and propensity score analyses were used to evaluate factors associated with treatment choice and survival. Results: In total, 3879 cases (74%) underwent cystectomy and 1380 (26%) were treated with primary radiotherapy. Cystectomy use increased over time (66, 75, 78%), whereas radiotherapy decreased (34, 25, 22%), P",

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T2 - A population-based outcomes study

AU - Booth, C. M.

AU - Siemens, D. R.

AU - Li, G.

AU - Peng, Y.

AU - Kong, W.

AU - Berman, D. M.

AU - Mackillop, W. J.

PY - 2014

Y1 - 2014

N2 - Aims: Definitive therapy of bladder cancer involves cystectomy or radiotherapy; controversy exists regarding optimal management. Here we describe the management and outcomes of patients treated in routine practice. Materials and methods: Treatment records were linked to the Ontario Cancer Registry to identify all cases of bladder cancer in Ontario treated with cystectomy or radiotherapy in 1994-2008. Practice patterns are described in three study periods: 1994-1998, 1999-2003, 2004-2008. Logistic regression, Cox model and propensity score analyses were used to evaluate factors associated with treatment choice and survival. Results: In total, 3879 cases (74%) underwent cystectomy and 1380 (26%) were treated with primary radiotherapy. Cystectomy use increased over time (66, 75, 78%), whereas radiotherapy decreased (34, 25, 22%), P

AB - Aims: Definitive therapy of bladder cancer involves cystectomy or radiotherapy; controversy exists regarding optimal management. Here we describe the management and outcomes of patients treated in routine practice. Materials and methods: Treatment records were linked to the Ontario Cancer Registry to identify all cases of bladder cancer in Ontario treated with cystectomy or radiotherapy in 1994-2008. Practice patterns are described in three study periods: 1994-1998, 1999-2003, 2004-2008. Logistic regression, Cox model and propensity score analyses were used to evaluate factors associated with treatment choice and survival. Results: In total, 3879 cases (74%) underwent cystectomy and 1380 (26%) were treated with primary radiotherapy. Cystectomy use increased over time (66, 75, 78%), whereas radiotherapy decreased (34, 25, 22%), P

KW - Bladder cancer

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KW - Health services

KW - Outcomes

KW - Quality of care

KW - Radiation

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Curative therapy for bladder cancer in routine clinical practice: A population-based outcomes study

Abstract

Keywords

ASJC Scopus subject areas

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