Cumulus Cells and their Associations with Immune Functions

Ping Xia, Clement Leung Kwok Chan

Research output: Contribution to journalReview articlepeer-review


The recent progress in the association of cumulus cells with immune functions is a largely ignored area. With over 350 million new sexually transmitted infections occurring annually in adults of reproductive age, we feel the need to explore more about how the cumulus cells defend themselves and protect the oocytes during the development through the ovulation period. Application of assisted reproductive technologies allows scientists to study and better understand cumulus cells. There are still many immune factors to be taken into consideration to optimize the oocyte quality besides ovarian stimulations. The objective of this review is to summarize the key elements of cumulus cells and their association with the immune function.

Original languageEnglish (US)
Pages (from-to)59-63
Number of pages5
JournalReproductive and Developmental Medicine
Issue number1
StatePublished - Mar 25 2018


  • Cumulus Cells
  • Follicles
  • Immune Function

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology


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