Cumulative risk of Alzheimer-like dementia in relatives of autopsy-confirmed cases of Alzheimer's disease

L. B. Hocking, John C.S. Breitner

Research output: Contribution to journalArticle


The cumulative risk of Alzheimer-like dementia (AD) was investigated in first-degree relatives (n = 176) of 35 probands with autopsy-confirmed clinical diagnoses of Alzheimer's disease. Seventeen of the 176 first-degree relatives showed evidence of AD. Cumulative morbid risk for the first-degree relatives was estimated to be 28.8%. This result is broadly consistent with previously reported studies, and affirms the presence of substantial disease risk in close relatives of those with Alzheimer's disease

Original languageEnglish (US)
Pages (from-to)355-356
Number of pages2
Issue number6
Publication statusPublished - 1995
Externally publishedYes



  • Alzheimer's disease
  • Dementia

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Neuropsychology and Physiological Psychology

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