CTLA-4 inhibitor: Ipilimumab for the treatment of NSCLC

Julie R. Brahmer

doi:10.2217/EBO.12.28

CTLA-4 inhibitor: Ipilimumab for the treatment of NSCLC

Julie R. Brahmer

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The approval of ipilimumab for the treatment of melanoma is a major step forward in cancer immunotherapy. The randomized Phase II trials yielded improvement in irPFS in both small-cell lung cancer and non-squamous-cell lung cancer patients treated with two cycles of chemotherapy followed by chemotherapy combined with ipilimumab. Ipilimumab is currently being evaluated for the treatment of squamous-cell lung cancer and small-cell lung cancer.

Original language	English (US)
Title of host publication	Targeted Therapies for Non-Small-Cell Lung Cancer
Publisher	Future Medicine Ltd.
Pages	47-54
Number of pages	8
ISBN (Electronic)	9781780840468
ISBN (Print)	9781780841236
DOIs	https://doi.org/10.2217/EBO.12.28
State	Published - Oct 1 2012

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ASJC Scopus subject areas

Medicine(all)

Cite this

Brahmer, J. R. (2012). CTLA-4 inhibitor: Ipilimumab for the treatment of NSCLC. In Targeted Therapies for Non-Small-Cell Lung Cancer (pp. 47-54). Future Medicine Ltd.. https://doi.org/10.2217/EBO.12.28

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Access to Document

10.2217/EBO.12.28