CTLA-4 inhibitor: Ipilimumab for the treatment of NSCLC

Research output: Chapter in Book/Report/Conference proceedingChapter


The approval of ipilimumab for the treatment of melanoma is a major step forward in cancer immunotherapy. The randomized Phase II trials yielded improvement in irPFS in both small-cell lung cancer and non-squamous-cell lung cancer patients treated with two cycles of chemotherapy followed by chemotherapy combined with ipilimumab. Ipilimumab is currently being evaluated for the treatment of squamous-cell lung cancer and small-cell lung cancer.

Original languageEnglish (US)
Title of host publicationTargeted Therapies for Non-Small-Cell Lung Cancer
PublisherFuture Medicine Ltd.
Number of pages8
ISBN (Electronic)9781780840468
ISBN (Print)9781780841236
StatePublished - Oct 1 2012

ASJC Scopus subject areas

  • Medicine(all)


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