CT scan and neuropsychological correlates of Alzheimer's Disease and Huntington's Disease

Amy E. Veroff; Godfrey D. Pearlson; Hyo S. Ahn

doi:10.1016/0278-2626(82)90015-X

CT scan and neuropsychological correlates of Alzheimer's Disease and Huntington's Disease

Amy E. Veroff, Godfrey D. Pearlson, Hyo S. Ahn

School of Medicine

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

"Cortical" and "subcortical" dementia syndromes differ in areas of primary neuropathology and clinical characteristics. Conventional CT scan interpretation, visual inspection of pictures, has not been useful in studying dementia. Recent studies of the digitally stored CT attenuation values have found systematic variations with normal aging and aphasia subtypes. In this study of numerical CT scan information in four Alzheimer's Disease and two Huntington's Disease patients, a double dissociation of frontal and temporal lobe density values was found, and a significant correlation was found between left temporal lobe density and verbal ability measures in the Alzheimer's Disease patients.

Original language	English (US)
Pages (from-to)	177-184
Number of pages	8
Journal	Brain and Cognition
Volume	1
Issue number	2
DOIs	https://doi.org/10.1016/0278-2626(82)90015-X
State	Published - Apr 1982

ASJC Scopus subject areas

Neuropsychology and Physiological Psychology
Experimental and Cognitive Psychology
Developmental and Educational Psychology
Arts and Humanities (miscellaneous)
Cognitive Neuroscience

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10.1016/0278-2626(82)90015-X

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title = "CT scan and neuropsychological correlates of Alzheimer's Disease and Huntington's Disease",

abstract = "{"}Cortical{"} and {"}subcortical{"} dementia syndromes differ in areas of primary neuropathology and clinical characteristics. Conventional CT scan interpretation, visual inspection of pictures, has not been useful in studying dementia. Recent studies of the digitally stored CT attenuation values have found systematic variations with normal aging and aphasia subtypes. In this study of numerical CT scan information in four Alzheimer's Disease and two Huntington's Disease patients, a double dissociation of frontal and temporal lobe density values was found, and a significant correlation was found between left temporal lobe density and verbal ability measures in the Alzheimer's Disease patients.",

author = "Veroff, {Amy E.} and Pearlson, {Godfrey D.} and Ahn, {Hyo S.}",

note = "Funding Information: This research was supported in part by NINCDS Grant 1POlNS 16375-01 (Baltimore Huntington{\textquoteright}s Disease Center without Walls). The authors wish to thank Drs. Arthur Rosenbaum and Paul R. McHugh, and M. E. Gunning for their technical advice and encouragement. Send reprint requests to Amy E. Veroff, Ph.D., Neuropsychology Service, Casa Colina Hospital, 255 East Bonita Ave., Pomona, CA 91767.",

year = "1982",

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doi = "10.1016/0278-2626(82)90015-X",

language = "English (US)",

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journal = "Brain and Cognition",

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T1 - CT scan and neuropsychological correlates of Alzheimer's Disease and Huntington's Disease

AU - Veroff, Amy E.

AU - Pearlson, Godfrey D.

AU - Ahn, Hyo S.

N1 - Funding Information: This research was supported in part by NINCDS Grant 1POlNS 16375-01 (Baltimore Huntington’s Disease Center without Walls). The authors wish to thank Drs. Arthur Rosenbaum and Paul R. McHugh, and M. E. Gunning for their technical advice and encouragement. Send reprint requests to Amy E. Veroff, Ph.D., Neuropsychology Service, Casa Colina Hospital, 255 East Bonita Ave., Pomona, CA 91767.

PY - 1982/4

Y1 - 1982/4

N2 - "Cortical" and "subcortical" dementia syndromes differ in areas of primary neuropathology and clinical characteristics. Conventional CT scan interpretation, visual inspection of pictures, has not been useful in studying dementia. Recent studies of the digitally stored CT attenuation values have found systematic variations with normal aging and aphasia subtypes. In this study of numerical CT scan information in four Alzheimer's Disease and two Huntington's Disease patients, a double dissociation of frontal and temporal lobe density values was found, and a significant correlation was found between left temporal lobe density and verbal ability measures in the Alzheimer's Disease patients.

AB - "Cortical" and "subcortical" dementia syndromes differ in areas of primary neuropathology and clinical characteristics. Conventional CT scan interpretation, visual inspection of pictures, has not been useful in studying dementia. Recent studies of the digitally stored CT attenuation values have found systematic variations with normal aging and aphasia subtypes. In this study of numerical CT scan information in four Alzheimer's Disease and two Huntington's Disease patients, a double dissociation of frontal and temporal lobe density values was found, and a significant correlation was found between left temporal lobe density and verbal ability measures in the Alzheimer's Disease patients.

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CT scan and neuropsychological correlates of Alzheimer's Disease and Huntington's Disease

Abstract

ASJC Scopus subject areas

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