CT evaluation of cervical cancer

Spectrum of disease

Harpreet K. Pannu, Frank M. Corl, Elliot K Fishman

Research output: Contribution to journalArticle

Abstract

Invasive cervical cancer is the third most common gynecologic malignancy. The prognosis is based on the stage, size, and histologic grade of the primary tumor and the status of the lymph nodes. Assessment of the stage of disease is important in determining whether the patient may benefit from surgery or will receive radiation therapy. The official clinical staging system of the International Federation of Gynecology and Obstetrics has led to errors of 65%-90% in stage III and IV disease; the result has been unofficial extended staging with cross-sectional imaging modalities such as computed tomography (CT). CT is useful in staging advanced disease and in monitoring patients for recurrence. The primary tumor is heterogeneous and hypoattenuating relative to normal stroma on contrast material-enhanced scans. Obliteration of the periureteral fat plane and a soft-tissue mass are the most reliable signs of parametrial extension. Less than 3 mm separation of the tumor from the pelvic muscles and vascular encasement are signs of pelvic side wall invasion. Lymphatic spread is along the external and internal iliac nodal chains and the presacral route to the paraaortic nodes. Distant metastases are seen with primary or recurrent disease and can involve the liver, lung, and bone.

Original languageEnglish (US)
Pages (from-to)1155-1168
Number of pages14
JournalRadiographics : a review publication of the Radiological Society of North America, Inc
Volume21
Issue number5
StatePublished - Sep 2001

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Uterine Cervical Neoplasms
Tomography
Neoplasms
Physiologic Monitoring
Gynecology
Contrast Media
Obstetrics
Blood Vessels
Radiotherapy
Lymph Nodes
Fats
Neoplasm Metastasis
Bone and Bones
Recurrence
Muscles
Lung
Liver

Keywords

  • Uterine neoplasms, CT, 854.12115
  • Uterine neoplasms, diagnosis, 854.32
  • Uterine neoplasms, metastases, **. 33 2
  • Uterine neoplasms, staging, 854.32

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

CT evaluation of cervical cancer : Spectrum of disease. / Pannu, Harpreet K.; Corl, Frank M.; Fishman, Elliot K.

In: Radiographics : a review publication of the Radiological Society of North America, Inc, Vol. 21, No. 5, 09.2001, p. 1155-1168.

Research output: Contribution to journalArticle

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