CT angiographic evaluation of genetic vascular disease: Role in detection, staging, and management of complex vascular pathologic conditions

Research output: Contribution to journalReview article

Abstract

OBJECTIVE. Arterial dissection and aneurysm rupture are significant sources of morbidity and mortality in patients with connective tissue diseases. This article provides a detailed analysis of cardiovascular involvement in Marfan syndrome, Loeys-Dietz syndrome, and vascular Ehlers-Danlos syndrome. CONCLUSION. Although these syndromes share some overlapping features, they have discriminating clinical and imaging features, and knowledge of these features enables the radiologist to aid the referring clinician in making the correct diagnosis.

Original languageEnglish (US)
Pages (from-to)1120-1129
Number of pages10
JournalAmerican Journal of Roentgenology
Volume202
Issue number5
DOIs
StatePublished - May 2014

Keywords

  • Aneurysm
  • CT angiography
  • Ehlers-Danlos syndrome
  • Loeys-Dietz syndrome
  • Marfan syndrome

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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