TY - JOUR
T1 - CT and MR imaging in staging non-small cell bronchogenic carcinoma
T2 - Report of the radiologic diagnostic oncology group
AU - Webb, W. Richard
AU - Gatsonis, Constantine
AU - Zerhouni, Elias A.
AU - Heelan, Robert T.
AU - Glazer, Gary M.
AU - Francis, Isaac R.
AU - McNeil, Barbara J.
PY - 1991/3
Y1 - 1991/3
N2 - The accuracies of magnetic resonance (MR) imaging and computed tomography (CT) in determining tumor classification and assessing mediastinal node metastases were compared in a prospective cooperative study of 170 patients with non-small cell bronchogenic carcinoma. The sensitivity of CT in distinguishing T3-T4 tumors from T0-T2 tumors was 63%; specificity was 84%. These values for MR imaging were not significantly different (56% and 80%). With receiver operating characteristic (ROC) analysis, no difference existed between the accuracies of CT and MR imaging in diagnosis of bronchial involvement or chest wall invasion, but MR imaging was significantly more accurate than CT (P = .047) in diagnosis of mediastinal invasion. Lymph node sampling was performed in 155 patients (642 node stations). Cancerous nodes were found in 14% of stations in 21% of patients. There was no significant difference between the accuracies of CT and MR imaging in detecting mediastinal node metastases (N2 or N3); the sensitivities were 52% and 48%, respectively, and specificities were 69% and 64%. ROC analysis also showed no difference between CT and MR imaging.
AB - The accuracies of magnetic resonance (MR) imaging and computed tomography (CT) in determining tumor classification and assessing mediastinal node metastases were compared in a prospective cooperative study of 170 patients with non-small cell bronchogenic carcinoma. The sensitivity of CT in distinguishing T3-T4 tumors from T0-T2 tumors was 63%; specificity was 84%. These values for MR imaging were not significantly different (56% and 80%). With receiver operating characteristic (ROC) analysis, no difference existed between the accuracies of CT and MR imaging in diagnosis of bronchial involvement or chest wall invasion, but MR imaging was significantly more accurate than CT (P = .047) in diagnosis of mediastinal invasion. Lymph node sampling was performed in 155 patients (642 node stations). Cancerous nodes were found in 14% of stations in 21% of patients. There was no significant difference between the accuracies of CT and MR imaging in detecting mediastinal node metastases (N2 or N3); the sensitivities were 52% and 48%, respectively, and specificities were 69% and 64%. ROC analysis also showed no difference between CT and MR imaging.
KW - Computed tomography (CT), comparative studies
KW - Lung neoplasms, CT, 60.211
KW - Lung neoplasms, MR studies, 60.1214
KW - Lung neoplasms, staging, 60.321
KW - Magnetic resonance (MR), comparative studies
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UR - http://www.scopus.com/inward/citedby.url?scp=0026012812&partnerID=8YFLogxK
U2 - 10.1148/radiology.178.3.1847239
DO - 10.1148/radiology.178.3.1847239
M3 - Article
C2 - 1847239
AN - SCOPUS:0026012812
VL - 178
SP - 705
EP - 713
JO - Radiology
JF - Radiology
SN - 0033-8419
IS - 3
ER -