CSF Cholinesterase Activity in Gilles de la Tourette's Syndrome

Harvey S. Singer; Leslie Oshida; Joseph T. Coyle

doi:10.1001/archneur.1984.04050180078022

CSF Cholinesterase Activity in Gilles de la Tourette's Syndrome

Harvey S. Singer, Leslie Oshida, Joseph T. Coyle

Johns Hopkins Hospital

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Cerebrospinal fluid acetylcholinesterase (AChE) activity was studied as a possible marker for central cholinergic neuronal function in seven patients with Gilles de la Tourette's syndrome. No significant differences were found between CSF AChE activity in untreated or haloperidol-treated patients and control populations. These data do not appear to support a pathophysiologic association between the cholinergic system and Gilles de la Tourette's syndrome.

Original language	English (US)
Pages (from-to)	756-757
Number of pages	2
Journal	Archives of neurology
Volume	41
Issue number	7
DOIs	https://doi.org/10.1001/archneur.1984.04050180078022
State	Published - Jul 1984

ASJC Scopus subject areas

Arts and Humanities (miscellaneous)
Clinical Neurology

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abstract = "Cerebrospinal fluid acetylcholinesterase (AChE) activity was studied as a possible marker for central cholinergic neuronal function in seven patients with Gilles de la Tourette's syndrome. No significant differences were found between CSF AChE activity in untreated or haloperidol-treated patients and control populations. These data do not appear to support a pathophysiologic association between the cholinergic system and Gilles de la Tourette's syndrome.",

author = "Singer, {Harvey S.} and Leslie Oshida and Coyle, {Joseph T.}",

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AU - Oshida, Leslie

AU - Coyle, Joseph T.

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AB - Cerebrospinal fluid acetylcholinesterase (AChE) activity was studied as a possible marker for central cholinergic neuronal function in seven patients with Gilles de la Tourette's syndrome. No significant differences were found between CSF AChE activity in untreated or haloperidol-treated patients and control populations. These data do not appear to support a pathophysiologic association between the cholinergic system and Gilles de la Tourette's syndrome.

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CSF Cholinesterase Activity in Gilles de la Tourette's Syndrome

Abstract

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