CS antigen localization in malaria vectors: hypothetical refractoriness to transmission observed in the field.

S. Lombardi, F. Esposito, F. Zavala, L. Lamizana, P. Rossi, G. Sabatinelli, R. S. Nussenzweig, M. Coluzzi

Research output: Contribution to journalArticlepeer-review

Abstract

Indoor resting Anopheles gambiae s.l. were collected in two villages near Ouagadougou, Burkina Faso, and processed to investigate the presence and distribution of Plasmodium sporozoites. Salivary glands were dissected, examined by phase contrast microscopy and further processed by IRMA in order to reveal the presence of the circumsporozoite (CS) antigen of P. falciparum. The corresponding thoraces were homogenized and processed by IRMA. In the village characterized by the higher inoculation rate more than 40% of the infected mosquitoes were not found infective since CS antigen was detected in the thorax in absence of sporozoites and CS antigen in the corresponding salivary glands.

Original languageEnglish (US)
Pages (from-to)113-116
Number of pages4
JournalParassitologia
Volume28
Issue number2-3
StatePublished - 1986
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology

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