Abstract
Crystallographic studies of liganded and unliganded forms of recombinant and chemically-crosslinked forms of human hemoglobin have been undertaken to assist in the development of artificial hemoglobin-based oxygen carriers. The crystal structure solution of each variant involves the collection of high resolution x-ray data using an electronic area detector followed by difference Fourier interpretation, alteration of the starting model followed by restrained least-squares refinement. These will then be described and compared with natural and other hemoglobins.
| Original language | English (US) |
|---|---|
| Pages (from-to) | A101 |
| Journal | Artificial Cells, Blood Substitutes, and Immobilization Biotechnology |
| Volume | 22 |
| Issue number | 5 |
| State | Published - Nov 1994 |
| Externally published | Yes |
| Event | Proceedings of the 11th Congress of the International Society for Artificial Cells, Blood Substitutes and Immobilization Biotechnology, (ISABI) - Boston, MA, USA Duration: Jul 24 1994 → Jul 27 1994 |
ASJC Scopus subject areas
- Biotechnology
- Biomedical Engineering