@article{5b3e3ffc53fc40878e9cc4a9521e16ac,
title = "Cryptococcal (torular) retinitis. A clinicopathologic case report",
abstract = "Clinicopathologic findings in a case of bilateral intraocular cryptococcosis are reported. Involvement of the retina and the leptomeningeal sheaths of the optic nerves was associated with a disseminated cryptococcal infection that affected the brain and meninges, suggesting that extension to intraocular structures from the central nervous system was by way of the leptomeningeal sheaths of the optic nerves. This is the second histopathologically proven case of cryptococcal neuroretinitis to be recorded, and it is one of 13 proven cases of intraocular cryptococcosis. Leukokoria in the absence of lens changes was an unusual finding. This patient also had systemic lupus erythematosus and had been on prolonged systemic corticosteroid therapy.",
author = "Khodadoust, {Ali A.} and Payne, {John W.}",
note = "Funding Information: In early June, 1967, she had had an ocular examination in the Wilmer eye clinic. At that time her fundi and vision were normal. On her final admission in late July, the examining physician had noted a pigmented area near the macula in her right eye and a large whitish lesion in the posterior pole of her left fundus. On July 28th, she was seen by an ophthalmologist. She gave a vague history of loss of vision in her left eye for one month and recent problems with central vision in her right eye. Because she was too ill, her visual acuity could not be accurately assessed. The eyes were prominent, with moderate conjunctival chemosis bilaterally and leukokoria on the left (fig. 1). On ophthalmoscopic examination of the left eye, the disc and vessels were normal. The posterior pole was involved by an intensely white, elevated chorioretinal lesion about 10 to 12 disc diameters in size (fig. 2). This lesion was thought to be a cryptococcal abscess. In the right eye the disc and vessels were also normal, but there was a flat, small, grayish lobulated lesion in the retina involving the macular area and, just temporal to From The Wilmer Ophthalmological Institute, The Johns Hopkins University School of Medicine. This work was supported in part by USPHS Training Grant No. NB-05217 from the National Institute of Neurological Diseases and Blindness, National Institutes of Health. ♦Present address : Department of Ophthalmology, Pahlavi University Medical School, Shiraz, Iran. Fig. 1 (Khodadoust and Payne). Prominent eyes, Reprint requests to John W. Payne, M.D., 14 moderate conjunctival chemosis more marked on West Mt. Vernon Place, Baltimore, Maryland 21201. the left side and leukokoria on the left.",
year = "1969",
month = may,
doi = "10.1016/S0002-9394(69)91001-0",
language = "English (US)",
volume = "67",
pages = "745--750",
journal = "American journal of ophthalmology",
issn = "0002-9394",
publisher = "Elsevier USA",
number = "5",
}