Cryptococcal panniculitis in an immunocompromised patient: A case report and review of the literature

Rachel Abuav, Laura Y. McGirt, Rebecca A. Kazin

Research output: Contribution to journalArticle

Abstract

Cryptococcus neoformans is a dimorphic fungus known to cause disease predominately in immunocompromised patients. It is not uncommon for cryptococcal disease to manifest within the cutaneous tissues of these patients, and it can have drastically varied presentations, from ulcerated nodules to a more subtle cellulitis. We present a patient who underwent a cardiac transplant and developed a fever and mildly erythematous, indurated plaques on his legs and flank several years later. Skin biopsy revealed cryptococcal panniculitis and C neoformans subsequently grew from both the biopsy culture and the cerebrospinal fluid (CSF). This case report highlights the varied and subtle presentations of cutaneous cryptococcosis in immunocompromised patients and encourages a high index of suspicion for this potentially fatal disease in the setting of immunosuppression.

Original languageEnglish (US)
Pages (from-to)303-306
Number of pages4
JournalCutis
Volume85
Issue number6
StatePublished - Jun 2010

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Panniculitis
Immunocompromised Host
Skin
Biopsy
Cryptococcosis
Cryptococcus neoformans
Cellulitis
Immunosuppression
Cerebrospinal Fluid
Leg
Fungi
Fever
Transplants

ASJC Scopus subject areas

  • Dermatology

Cite this

Cryptococcal panniculitis in an immunocompromised patient : A case report and review of the literature. / Abuav, Rachel; McGirt, Laura Y.; Kazin, Rebecca A.

In: Cutis, Vol. 85, No. 6, 06.2010, p. 303-306.

Research output: Contribution to journalArticle

Abuav, R, McGirt, LY & Kazin, RA 2010, 'Cryptococcal panniculitis in an immunocompromised patient: A case report and review of the literature', Cutis, vol. 85, no. 6, pp. 303-306.
Abuav, Rachel ; McGirt, Laura Y. ; Kazin, Rebecca A. / Cryptococcal panniculitis in an immunocompromised patient : A case report and review of the literature. In: Cutis. 2010 ; Vol. 85, No. 6. pp. 303-306.
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