Cryotherapy for Barrett's Esophagus: Who, How, and Why?

Ann M. Chen, Pankaj J. Pasricha

Research output: Contribution to journalReview article


Cryotherapy is a noncontact ablation method that has long been used clinically in the treatment of a wide variety of malignant and premalignant diseases. The relative ease of use and unique mechanisms of cellular destruction make cryotherapy particularly attractive for the eradication of dysplastic Barrett's esophagus. Currently, liquid nitrogen and carbon dioxide are the most common cryogens used. Preliminary data with these agents have shown high efficacy in the reversal of dysplastic Barrett mucosa and excellent safety profiles. Intense investigation on cryotherapy ablation of Barrett's esophagus is ongoing.

Original languageEnglish (US)
Pages (from-to)111-118
Number of pages8
JournalGastrointestinal Endoscopy Clinics of North America
Issue number1
StatePublished - Jan 1 2011



  • Barrett's esophagus
  • Cryoablation
  • Cryotherapy

ASJC Scopus subject areas

  • Gastroenterology

Cite this