Cryotherapy enhances intravitreal dispersion of viable retinal pigment epithelial cells

Peter A Campochiaro, Ian H. Kaden, Jesus Vidaurri Leal, Bert M. Glaser

Research output: Contribution to journalArticle

Abstract

Proliferative vitreoretinopathy (PVR) is the most common cause of failure in retinal reattachment surgery. Giant retinal tears are associated with a particularly high incidence of PVR. It involves the formation of cellular membranes that contract and cause traction retinal detachments. Retinal pigment epithelial (RPE) cells are a major component of these cellular membranes. Displacement of viable RPE cells from their normal position into the vitreous cavity is necessary for membrane formation to occur. This study demonstrates that cryotherapy, but not diathermy, enhances intravitreal dispersion of viable RPE cells in bovine eyes in vitro. This suggests that in some circumstances, excessive cryotherapy may play an exacerbating role in the initiation of PVR.

Original languageEnglish (US)
Pages (from-to)434-436
Number of pages3
JournalArchives of Ophthalmology
Volume103
Issue number3
DOIs
StatePublished - 1985

Fingerprint

Proliferative Vitreoretinopathy
Cryotherapy
Retinal Pigments
Epithelial Cells
Membranes
Diathermy
Retinal Perforations
Traction
Retinal Detachment
Contracts
Incidence

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Cryotherapy enhances intravitreal dispersion of viable retinal pigment epithelial cells. / Campochiaro, Peter A; Kaden, Ian H.; Vidaurri Leal, Jesus; Glaser, Bert M.

In: Archives of Ophthalmology, Vol. 103, No. 3, 1985, p. 434-436.

Research output: Contribution to journalArticle

Campochiaro, Peter A ; Kaden, Ian H. ; Vidaurri Leal, Jesus ; Glaser, Bert M. / Cryotherapy enhances intravitreal dispersion of viable retinal pigment epithelial cells. In: Archives of Ophthalmology. 1985 ; Vol. 103, No. 3. pp. 434-436.
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