Cryoablation of Osteoid Osteoma in the Pediatric and Adolescent Population

Morgan J. Whitmore, C. Matthew Hawkins, J. David Prologo, Kelley W. Marshall, Jorge A. Fabregas, Douglas B. Yim, David Monson, Shervin V. Oskouei, Nicholas D. Fletcher, Roger S. Williams

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Abstract

Purpose To evaluate the technical feasibility and clinical efficacy of osteoid osteoma (OO) cryoablation in a large, pediatric/adolescent cohort. Materials and Methods An electronic medical record and imaging archive review was performed to identify all cryoablations performed for OOs between 2011 and 2015 at a single tertiary care pediatric hospital. The subsequent analysis included 29 patients with suspected OOs treated by cryoablation (age range, 3-18 y; mean age, 11.3 y; 17 boys; 12 girls). Conventional CT guidance was used in 22 procedures; cone-beam CT guidance was used in 7 procedures. Follow-up data were obtained via a standardized telephone questionnaire (23/29 patients; 79.3%) and clinical notes (5/29 patients; 17.2%). One patient was lost to follow-up. Results Technical success was achieved in 100% of patients (29/29). Immediate clinical success (cessation of pain and nonsteroidal antiinflammatory drug [NSAID] use within 1 mo after the procedure) was achieved in 27/28 patients (96.4%). Short-term clinical success (cessation of pain and NSAID use for > 3 mo after the procedure) was achieved in 24/25 patients (96%). Long-term clinical success (cessation of pain and NSAID use for > 12 mo after the procedure) was achieved in 19/21 patients (90.5%). Median pain scale score before the procedure was 10 (range, 5-10); median pain scale score after the procedure was 0 (range, 0-8; P <.0001). There were 6 minor complications (21%) and no major complications. Conclusion Image-guided cryoablation is a technically feasible, clinically efficacious therapeutic option for children and adolescents with symptomatic OO.

Original languageEnglish (US)
Pages (from-to)232-237
Number of pages6
JournalJournal of Vascular and Interventional Radiology
Volume27
Issue number2
DOIs
StatePublished - Feb 1 2016

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ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Whitmore, M. J., Hawkins, C. M., Prologo, J. D., Marshall, K. W., Fabregas, J. A., Yim, D. B., Monson, D., Oskouei, S. V., Fletcher, N. D., & Williams, R. S. (2016). Cryoablation of Osteoid Osteoma in the Pediatric and Adolescent Population. Journal of Vascular and Interventional Radiology, 27(2), 232-237. https://doi.org/10.1016/j.jvir.2015.10.005