Cross-reactivity of non-Aspergillus fungal species in the Aspergillus galactomannan enzyme immunoassay

Jessica R. Cummings, Ginger R. Jamison, Jan W. Boudreaux, Merry J. Howles, Thomas J. Walsh, Randall T. Hayden

Research output: Contribution to journalArticle

Abstract

The Aspergillus galactomannan enzyme-linked immunosorbant assay (EIA) has been demonstrated to facilitate rapid and sensitive detection of invasive aspergillosis. However, test specificity has not been fully evaluated in non-Aspergillus fungal species. Of 53 fungal isolates, cross-reactivity was observed with 5 non-Aspergillus spp.: Blastomyces dermatitidis, Nigrospora oryzae, Paecilomyces lilacinus, Penicillium chrysogenum, and Trichothecium roseum.

Original languageEnglish (US)
Pages (from-to)113-115
Number of pages3
JournalDiagnostic Microbiology and Infectious Disease
Volume59
Issue number1
DOIs
StatePublished - Sep 2007
Externally publishedYes

Fingerprint

Blastomyces
Paecilomyces
Penicillium chrysogenum
Aspergillosis
Aspergillus
Immunoenzyme Techniques
Enzymes
galactomannan
Oryza

Keywords

  • Antigen
  • Aspergillus
  • Galactomannan

ASJC Scopus subject areas

  • Infectious Diseases
  • Immunology and Allergy
  • Virology
  • Parasitology
  • Microbiology
  • Immunology
  • Applied Microbiology and Biotechnology

Cite this

Cross-reactivity of non-Aspergillus fungal species in the Aspergillus galactomannan enzyme immunoassay. / Cummings, Jessica R.; Jamison, Ginger R.; Boudreaux, Jan W.; Howles, Merry J.; Walsh, Thomas J.; Hayden, Randall T.

In: Diagnostic Microbiology and Infectious Disease, Vol. 59, No. 1, 09.2007, p. 113-115.

Research output: Contribution to journalArticle

Cummings, Jessica R. ; Jamison, Ginger R. ; Boudreaux, Jan W. ; Howles, Merry J. ; Walsh, Thomas J. ; Hayden, Randall T. / Cross-reactivity of non-Aspergillus fungal species in the Aspergillus galactomannan enzyme immunoassay. In: Diagnostic Microbiology and Infectious Disease. 2007 ; Vol. 59, No. 1. pp. 113-115.
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