Cross-reactivity of non-Aspergillus fungal species in the Aspergillus galactomannan enzyme immunoassay

Jessica R. Cummings, Ginger R. Jamison, Jan W. Boudreaux, Merry J. Howles, Thomas J. Walsh, Randall T. Hayden

Research output: Contribution to journalArticle

Abstract

The Aspergillus galactomannan enzyme-linked immunosorbant assay (EIA) has been demonstrated to facilitate rapid and sensitive detection of invasive aspergillosis. However, test specificity has not been fully evaluated in non-Aspergillus fungal species. Of 53 fungal isolates, cross-reactivity was observed with 5 non-Aspergillus spp.: Blastomyces dermatitidis, Nigrospora oryzae, Paecilomyces lilacinus, Penicillium chrysogenum, and Trichothecium roseum.

Original languageEnglish (US)
Pages (from-to)113-115
Number of pages3
JournalDiagnostic Microbiology and Infectious Disease
Volume59
Issue number1
DOIs
StatePublished - Sep 1 2007

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Keywords

  • Antigen
  • Aspergillus
  • Galactomannan

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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