Craniofacial growth in Apert syndrome as measured by finite-element scaling analysis

J. T. Richtsmeier

Research output: Contribution to journalArticle

Abstract

A new tool for the study of biological form change is applied in a comparison of craniofacial growth in normal children and those affected with Apert syndrome. Using finite-element scaling analysis, the magnitude of size change during postnatal growth in the Apert sample was determined to be generally less than normal, and the magnitude of shape change was generally greater than normal. No consistent, statistically significant, alteration from normal growth was defined in the Apert sample, however. There appears to be no consistent effect on general cell and tissue proliferation in Apert syndrome. Rather, specific subpopulations of cells and tissues may be affected differentially over time.

Original languageEnglish (US)
Pages (from-to)50-56
Number of pages7
JournalActa Anatomica
Volume133
Issue number1
StatePublished - 1988

Fingerprint

Acrocephalosyndactylia
Finite Element Analysis
Growth
Cell Proliferation

ASJC Scopus subject areas

  • Anatomy

Cite this

Craniofacial growth in Apert syndrome as measured by finite-element scaling analysis. / Richtsmeier, J. T.

In: Acta Anatomica, Vol. 133, No. 1, 1988, p. 50-56.

Research output: Contribution to journalArticle

@article{8bdad8d045704ac3b29ea3ebbd86a512,
title = "Craniofacial growth in Apert syndrome as measured by finite-element scaling analysis",
abstract = "A new tool for the study of biological form change is applied in a comparison of craniofacial growth in normal children and those affected with Apert syndrome. Using finite-element scaling analysis, the magnitude of size change during postnatal growth in the Apert sample was determined to be generally less than normal, and the magnitude of shape change was generally greater than normal. No consistent, statistically significant, alteration from normal growth was defined in the Apert sample, however. There appears to be no consistent effect on general cell and tissue proliferation in Apert syndrome. Rather, specific subpopulations of cells and tissues may be affected differentially over time.",
author = "Richtsmeier, {J. T.}",
year = "1988",
language = "English (US)",
volume = "133",
pages = "50--56",
journal = "Cells Tissues Organs",
issn = "1422-6405",
publisher = "S. Karger AG",
number = "1",

}

TY - JOUR

T1 - Craniofacial growth in Apert syndrome as measured by finite-element scaling analysis

AU - Richtsmeier, J. T.

PY - 1988

Y1 - 1988

N2 - A new tool for the study of biological form change is applied in a comparison of craniofacial growth in normal children and those affected with Apert syndrome. Using finite-element scaling analysis, the magnitude of size change during postnatal growth in the Apert sample was determined to be generally less than normal, and the magnitude of shape change was generally greater than normal. No consistent, statistically significant, alteration from normal growth was defined in the Apert sample, however. There appears to be no consistent effect on general cell and tissue proliferation in Apert syndrome. Rather, specific subpopulations of cells and tissues may be affected differentially over time.

AB - A new tool for the study of biological form change is applied in a comparison of craniofacial growth in normal children and those affected with Apert syndrome. Using finite-element scaling analysis, the magnitude of size change during postnatal growth in the Apert sample was determined to be generally less than normal, and the magnitude of shape change was generally greater than normal. No consistent, statistically significant, alteration from normal growth was defined in the Apert sample, however. There appears to be no consistent effect on general cell and tissue proliferation in Apert syndrome. Rather, specific subpopulations of cells and tissues may be affected differentially over time.

UR - http://www.scopus.com/inward/record.url?scp=0023788080&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023788080&partnerID=8YFLogxK

M3 - Article

C2 - 3213406

AN - SCOPUS:0023788080

VL - 133

SP - 50

EP - 56

JO - Cells Tissues Organs

JF - Cells Tissues Organs

SN - 1422-6405

IS - 1

ER -