TY - JOUR
T1 - COVID-19 Testing, Epidemic Features, Hospital Outcomes, and Household Prevalence, New York State-March 2020
AU - New York State Coronavirus 2019 Response Team
AU - Rosenberg, Eli S.
AU - Dufort, Elizabeth M.
AU - Blog, Debra S.
AU - Hall, Eric W.
AU - Hoefer, Dina
AU - Backenson, Bryon P.
AU - Muse, Alison T.
AU - Kirkwood, James N.
AU - St. George, Kirsten
AU - Holtgrave, David R.
AU - Hutton, Brad J.
AU - Zucker, Howard A.
AU - Anand, Madhu
AU - Kaufman, Alison
AU - Kuhles, Daniel
AU - Maxted, Angie
AU - Newman, Alexandra
AU - Pulver, Wendy
AU - Smith, Lou
AU - Sommer, Jamie
AU - White, Jennifer
AU - Dean, Amy
AU - Derbyshire, Victoria
AU - Egan, Christina
AU - Fuschino, Meghan
AU - Griesemer, Sara
AU - Hull, Rene
AU - Lamson, Daryl
AU - Laplante, Jennifer
AU - McDonough, Kathleen
AU - Mitchell, Kara
AU - Musser, Kimberlee
AU - Nazarian, Elizabeth
AU - Popowich, Michael
AU - Taylor, Jill
AU - Walsh, Anne
AU - Amler, Sherlita
AU - Huang, Ada
AU - Recchia, Renee
AU - Whalen, Elizabeth
AU - Lewis, Elizabeth
AU - Friedman, Cynthia
AU - Carrera, Sandra
AU - Eisenstein, Lawrence
AU - Desimone, Ann
AU - Morne, Johanne
AU - Johnson, Megan
AU - Navarette, Kristen
AU - Kumar, Jessica
AU - Ostrowski, Stephanie
N1 - Publisher Copyright:
© 2020 The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.
PY - 2020/10/15
Y1 - 2020/10/15
N2 - Background: The US' coronavirus disease 2019 (COVID-19) epidemic has grown extensively since February 2020, with substantial associated hospitalizations and mortality; New York State has emerged as the national epicenter. We report on the extent of testing and test results during the month of March in New York State, along with risk factors, outcomes, and household prevalence among initial cases subject to in-depth investigations. Methods: Specimen collection for COVID-19 testing was conducted in healthcare settings, community-based collection sites, and by home testing teams. Information on demographics, risk factors, and hospital outcomes of cases was obtained through epidemiological investigations and an electronic medical records match, and summarized descriptively. Active testing of initial case's households enabled estimation of household prevalence. Results: During March in New York State, outside of New York City, a total of 47 326 persons tested positive for severe acute respiratory syndrome coronavirus 2, out of 141 495 tests (33% test-positive), with the highest number of cases located in the metropolitan region counties. Among 229 initial cases diagnosed through 12 March, by 30 March 13% were hospitalized and 2% died. Testing conducted among 498 members of these case's households found prevalent infection among 57%, excluding first-reported cases 38%. In these homes, we found a significant age gradient in prevalence, from 23% among those < 5 years to 68% among those ≥ 65 years (P <.0001). Conclusions: New York State faced a substantial and increasing COVID-19 outbreak during March 2020. The earliest cases had high levels of infection in their households and by the end of the month, the risks of hospitalization and death were high.
AB - Background: The US' coronavirus disease 2019 (COVID-19) epidemic has grown extensively since February 2020, with substantial associated hospitalizations and mortality; New York State has emerged as the national epicenter. We report on the extent of testing and test results during the month of March in New York State, along with risk factors, outcomes, and household prevalence among initial cases subject to in-depth investigations. Methods: Specimen collection for COVID-19 testing was conducted in healthcare settings, community-based collection sites, and by home testing teams. Information on demographics, risk factors, and hospital outcomes of cases was obtained through epidemiological investigations and an electronic medical records match, and summarized descriptively. Active testing of initial case's households enabled estimation of household prevalence. Results: During March in New York State, outside of New York City, a total of 47 326 persons tested positive for severe acute respiratory syndrome coronavirus 2, out of 141 495 tests (33% test-positive), with the highest number of cases located in the metropolitan region counties. Among 229 initial cases diagnosed through 12 March, by 30 March 13% were hospitalized and 2% died. Testing conducted among 498 members of these case's households found prevalent infection among 57%, excluding first-reported cases 38%. In these homes, we found a significant age gradient in prevalence, from 23% among those < 5 years to 68% among those ≥ 65 years (P <.0001). Conclusions: New York State faced a substantial and increasing COVID-19 outbreak during March 2020. The earliest cases had high levels of infection in their households and by the end of the month, the risks of hospitalization and death were high.
KW - COVID-19
KW - prevalence
KW - surveillance
KW - testing
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U2 - 10.1093/cid/ciaa549
DO - 10.1093/cid/ciaa549
M3 - Article
C2 - 32382743
AN - SCOPUS:85084617308
SN - 1058-4838
VL - 71
SP - 1953
EP - 1959
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
IS - 8
ER -