Abstract
Background: COVID-19 pandemic-related disruptions to EUS-based pancreatic cancer surveillance in high-risk individuals remain uncertain. Methods: Analysis of enrolled participants in the CAPS5 Study, a prospective multicenter study of pancreatic cancer surveillance in high-risk individuals. Results: Amongst 693 enrolled high-risk individuals under active surveillance, 108 (16%) had an EUS scheduled during the COVID-19 pandemic-related shutdown (median length of 78 days) in the spring of 2020, with 97% of these procedures being canceled. Of these canceled surveillance EUSs, 83% were rescheduled in a median of 4.1 months, however 17% were not rescheduled after 6 months follow-up. Prior history of cancer was associated with increased likelihood of rescheduling. To date no pancreatic cancer has been diagnosed among those whose surveillance was delayed. Conclusions: COVID-19 delayed pancreatic cancer surveillance with no adverse outcomes in efficiently rescheduled individuals. However, 1 in 6 high-risk individuals had not rescheduled surveillance, indicating the need for vigilance to ensure timely surveillance rescheduling.
Original language | English (US) |
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Pages (from-to) | 1048-1051 |
Number of pages | 4 |
Journal | Pancreatology |
Volume | 21 |
Issue number | 6 |
DOIs | |
State | Published - Sep 2021 |
Keywords
- COVID-19
- EUS
- Pancreatic cancer
- Surveillance
ASJC Scopus subject areas
- Endocrinology
- Endocrinology, Diabetes and Metabolism
- Hepatology