Could early septal involvement in the remodeling process be related to the advance hypertensive heart disease?

Fatih Yalçin, Caner Topaloglu, Nagehan Kuçukler, Mehmet Ofgeli, Theodore P. Abraham

Research output: Contribution to journalArticle


Quantitative imaging analyses showed an earlier septal wall involvement in hypertension. We planned to determine the effect of hypertension on regional myocardial performance index (MPI) in a hypertensive patient population. Methods: We evaluated 119 hypertensive patients who were divided into gr. I: 57 patients without left ventricular hypertrophy (LVH), (53.1. ±. 10. years), and gr. II: 62 patients with LVH (55.1. ±. 9. years) using conventional and tissue doppler imaging. They were compared with gr. III, a sex-age-matched normal control group (37 subjects, 53.0. ±. 10. years). Results: We detected basal septal and basal lateral contraction time (CT), isovolumetric CT and relaxation time (IVRT) and MPI. EF was 68. ±. 5 % in gr. I, 69. ±. 5 % in gr. II, 69. ±. 4 % in gr. III. LV mass index was 122. ±. 11. g/m2 in gr. I, 148. ±. 13. g/m2 in gr. II and 118. ±. 13. g/m2 in gr. III. Concentric LVH was detected in gr. II (relative wall thickness. =. 0.49. ±. 0.8). LV septal and lateral MPI were abnormal in both hypertensive groups (p.

Original languageEnglish (US)
Pages (from-to)141-145
Number of pages5
JournalIJC Heart and Vasculature
Publication statusPublished - Jun 1 2015



  • Hypertensive heart disease
  • Regional myocardial performance
  • Regional myocardial remodeling

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this