TY - JOUR
T1 - Cost-effectiveness of an intervention to prevent depression in at-risk teens
AU - Lynch, Frances L.
AU - Hornbrook, Mark
AU - Clarke, Gregory N.
AU - Perrin, Nancy
AU - Polen, Michael R.
AU - O'Connor, Elizabeth
AU - Dickerson, John
PY - 2005/11
Y1 - 2005/11
N2 - Contact: Depression is common in adolescent offspring of depressed parents and can be prevented, but adoption of prevention programs is dependent on the balance of their incremental costs and benefits. Objective: To examine the incremental cost-effectiveness of a group cognitive behavioral intervention to prevent depression in adolescent offspring of depressed parents. Design: Cost-effectiveness analysis of a recent randomized controlled trial. Setting: Kaiser Permanente Northwest, a large health maintenance organization. Participants: Teens 13 to 18 years old at risk for depression. Interventions: Usual care (n=49) or usual care plus a 15-session group cognitive therapy prevention program (n=45). Main Outcome Measures: Clinical outcomes were converted to depression-free days and quality-adjusted life-years. Total health maintenance organization costs, costs of services received in other sectors, and family costs were combined with clinical outcomes in a cost-effectiveness analysis comparing the intervention with usual care for 1 year after the intervention. Results: Average cost of the intervention was $1632, and total direct and indirect costs increased by $610 in the intervention group. However, the result was not statistically significant, suggesting a possible cost offset. Estimated incremental cost per depression-free day in the base-case analysis was $10 (95% confidence interval, -$13 to $52) or $9275 per quality-adjusted life-year (95% confidence interval, -$12 148 to $45 641). Conclusions: Societal cost-effectiveness of a brief prevention program to reduce the risk of depression in offspring of depressed parents is comparable to that of accepted depression treatments, and the program is cost-effective compared with other health interventions commonly covered in insurance contracts.
AB - Contact: Depression is common in adolescent offspring of depressed parents and can be prevented, but adoption of prevention programs is dependent on the balance of their incremental costs and benefits. Objective: To examine the incremental cost-effectiveness of a group cognitive behavioral intervention to prevent depression in adolescent offspring of depressed parents. Design: Cost-effectiveness analysis of a recent randomized controlled trial. Setting: Kaiser Permanente Northwest, a large health maintenance organization. Participants: Teens 13 to 18 years old at risk for depression. Interventions: Usual care (n=49) or usual care plus a 15-session group cognitive therapy prevention program (n=45). Main Outcome Measures: Clinical outcomes were converted to depression-free days and quality-adjusted life-years. Total health maintenance organization costs, costs of services received in other sectors, and family costs were combined with clinical outcomes in a cost-effectiveness analysis comparing the intervention with usual care for 1 year after the intervention. Results: Average cost of the intervention was $1632, and total direct and indirect costs increased by $610 in the intervention group. However, the result was not statistically significant, suggesting a possible cost offset. Estimated incremental cost per depression-free day in the base-case analysis was $10 (95% confidence interval, -$13 to $52) or $9275 per quality-adjusted life-year (95% confidence interval, -$12 148 to $45 641). Conclusions: Societal cost-effectiveness of a brief prevention program to reduce the risk of depression in offspring of depressed parents is comparable to that of accepted depression treatments, and the program is cost-effective compared with other health interventions commonly covered in insurance contracts.
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U2 - 10.1001/archpsyc.62.11.1241
DO - 10.1001/archpsyc.62.11.1241
M3 - Article
C2 - 16275811
AN - SCOPUS:27744473804
SN - 0003-990X
VL - 62
SP - 1241
EP - 1248
JO - Archives of general psychiatry
JF - Archives of general psychiatry
IS - 11
ER -