Corticosteroids in clinical and experimental lung transplantation

F. J. Veith, S. K. Koerner, S. Sprayregen, S. S. Siegelman, S. Blümcke, R. Crane, J. W. Hagstrom, M. L. Gliedman

Research output: Contribution to journalArticle

Abstract

Lung allograft rejection can usually be diagnosed by the appearance of infiltrates on plain chest roentgenograms when these are interpreted in the light of other clinical and bacteriologic information. Large pulsed i.v. doses of methylprednisolone were usually effective in reversing lung allograft rejection that occurred in immunosuppressed dogs. In 10 of 15 animals the presence of moderate to severe rejection and its effective reversal with treatment were documented with roentgenograms and histologic sections. This ability to reverse the manifestations of lung allograft rejection, when they occur, has helped in the management of human lung allograft recipients.

Original languageEnglish (US)
Pages (from-to)99-102
Number of pages4
JournalTransplantation proceedings
Volume7
Issue number1
StatePublished - Dec 1 1975

ASJC Scopus subject areas

  • Surgery
  • Transplantation

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    Veith, F. J., Koerner, S. K., Sprayregen, S., Siegelman, S. S., Blümcke, S., Crane, R., Hagstrom, J. W., & Gliedman, M. L. (1975). Corticosteroids in clinical and experimental lung transplantation. Transplantation proceedings, 7(1), 99-102.