Corticosteroids for prevention of adverse reactions to intravenous immune serum globulin infusions in hypogammaglobulinemic patients

Howard M. Lederman, Chaim M. Roifman, Sasson Lavi, Erwin W. Gelfand

Research output: Contribution to journalArticlepeer-review

Abstract

Severe adverse reactions to intravenous immune serum globulin occurred repeatedly in four of 10 hypogammaglobulinemic patients. Treatment-limiting symptoms included fever, chills, headache, hypertension, and chest pain. Pretreatment of patients with hydrocortisone immediately prior to infusion prevented subsequent adverse reactions and permitted these patients to receive immune serum globulin intravenously.

Original languageEnglish (US)
Pages (from-to)443-446
Number of pages4
JournalThe American journal of medicine
Volume81
Issue number3
DOIs
StatePublished - Sep 1986
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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