Corticosteroids for prevention of adverse reactions to intravenous immune serum globulin infusions in hypogammaglobulinemic patients

Howard M Lederman, Chaim M. Roifman, Sasson Lavi, Erwin W. Gelfand

Research output: Contribution to journalArticle

Abstract

Severe adverse reactions to intravenous immune serum globulin occurred repeatedly in four of 10 hypogammaglobulinemic patients. Treatment-limiting symptoms included fever, chills, headache, hypertension, and chest pain. Pretreatment of patients with hydrocortisone immediately prior to infusion prevented subsequent adverse reactions and permitted these patients to receive immune serum globulin intravenously.

Original languageEnglish (US)
Pages (from-to)443-446
Number of pages4
JournalAmerican Journal of Medicine
Volume81
Issue number3
DOIs
StatePublished - 1986
Externally publishedYes

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Serum Globulins
Intravenous Immunoglobulins
Immune Sera
Adrenal Cortex Hormones
Chills
Chest Pain
Headache
Hydrocortisone
Immunoglobulins
Fever
Hypertension
Therapeutics

ASJC Scopus subject areas

  • Nursing(all)

Cite this

Corticosteroids for prevention of adverse reactions to intravenous immune serum globulin infusions in hypogammaglobulinemic patients. / Lederman, Howard M; Roifman, Chaim M.; Lavi, Sasson; Gelfand, Erwin W.

In: American Journal of Medicine, Vol. 81, No. 3, 1986, p. 443-446.

Research output: Contribution to journalArticle

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