Corticosteroids as an adjunct to propranolol for infantile haemangiomas complicated by recalcitrant ulceration

E. Lie, Katherine Brown Puttgen

Research output: Contribution to journalArticle

Abstract

A small subset of patients with infantile haemangiomas (IHs) can present with serious complications, the most common of which is ulceration. Ulcerated IHs can be extremely painful and always result in scarring. Numerous studies support the efficacy and reduced side-effects of propranolol relative to systemic corticosteroids, which led to the adoption of propranolol as the mainstay of IH treatment. However, in certain cases of IH with complex ulceration, propranolol monotherapy may not be sufficient. In this case report, we present two cases that illustrate the effectiveness of the adjunctive use of oral corticosteroids for the treatment of select IHs with recalcitrant painful ulceration, which were refractory to conservative wound care, laser therapy and oral propranolol. We suggest a continuing niche role for the brief use of corticosteroids as an effective adjunct to oral propranolol in managing a subset of complex IHs complicated by intractable ulceration.

Original languageEnglish (US)
Pages (from-to)1064-1067
Number of pages4
JournalBritish Journal of Dermatology
Volume176
Issue number4
DOIs
StatePublished - Apr 1 2017

ASJC Scopus subject areas

  • Dermatology

Fingerprint Dive into the research topics of 'Corticosteroids as an adjunct to propranolol for infantile haemangiomas complicated by recalcitrant ulceration'. Together they form a unique fingerprint.

  • Cite this