Corticosteroids and increased risk of readmission after acute chest syndrome in children with sickle cell disease

John Strouse, Clifford M Takemoto, Jeffrey Keefer, Gregory J. Kato, James F Casella

Research output: Contribution to journalArticle

Abstract

Background. Acute chest syndrome (ACS) is a frequent cause of hospitalization and mortality in children with sickle cell disease. Transfusion is often required to prevent respiratory failure and treatment with dexamethasone may reduce the length of admission and the need for transfusions. We performed a retrospective cohort study to evaluate risk factors for readmission and prolonged hospitalization after different treatments for ACS. Procedure. We identified patients

Original languageEnglish (US)
Pages (from-to)1006-1012
Number of pages7
JournalPediatric Blood and Cancer
Volume50
Issue number5
DOIs
StatePublished - May 2008

Fingerprint

Acute Chest Syndrome
Sickle Cell Anemia
Adrenal Cortex Hormones
Hospitalization
Child Mortality
Respiratory Insufficiency
Dexamethasone
Cohort Studies
Retrospective Studies
Therapeutics

Keywords

  • Acute chest syndrome
  • Cohort study
  • Corticosteroids
  • Sickle cell disease
  • Transfusions

ASJC Scopus subject areas

  • Cancer Research
  • Pediatrics, Perinatology, and Child Health
  • Hematology

Cite this

Corticosteroids and increased risk of readmission after acute chest syndrome in children with sickle cell disease. / Strouse, John; Takemoto, Clifford M; Keefer, Jeffrey; Kato, Gregory J.; Casella, James F.

In: Pediatric Blood and Cancer, Vol. 50, No. 5, 05.2008, p. 1006-1012.

Research output: Contribution to journalArticle

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