Cortical centres underlying auditory temporal processing in humans

A PET study

Christian Brahe Pedersen, Frank Mirz, Therese Ovesen, Koichi Ishizu, Peter Johannsen, Stig Madsen, Albert Gjedde

Research output: Contribution to journalArticle

Abstract

We have used positron emission tomography (PET) to test a specific hypothesis of a neural system subserving auditory temporal processing (acoustical stimulus duration discrimination). Maps of the cerebral blood flow distribution during specific stimulations were obtained from five normally-hearing and otherwise healthy subjects. The auditory stimuli consisted of sounds of varying duration and of auditorily presented words in which the duration of the initial phoneme was manipulated. All stimuli alternated with conditions of silence in a subtraction paradigm. The blood flow distribution was mapped with O-15-labelled water. The results demonstrated that stimuli requiring recognizing, memorizing, or attending to specific target sounds during temporal processing generally resulted in significant activation of both frontal lobes and the parietal lobe in the right hemisphere. Based on these results, we hypothesise that a network consisting of anterior and posterior auditory attention and short-term memory sites subserves acoustical stimulus duration perception and analysis (auditory temporal processing).

Original languageEnglish (US)
Pages (from-to)30-37
Number of pages8
JournalAudiology
Volume39
Issue number1
StatePublished - Jan 2000
Externally publishedYes

Fingerprint

Positron-Emission Tomography
Cerebrovascular Circulation
Auditory Perception
Parietal Lobe
Frontal Lobe
Short-Term Memory
Hearing
Healthy Volunteers
Water
Discrimination (Psychology)

Keywords

  • Attention
  • Auditory temporal processing
  • Functional brain imaging
  • Memory
  • Parietal cortex
  • Prefrontal cortex

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Speech and Hearing

Cite this

Pedersen, C. B., Mirz, F., Ovesen, T., Ishizu, K., Johannsen, P., Madsen, S., & Gjedde, A. (2000). Cortical centres underlying auditory temporal processing in humans: A PET study. Audiology, 39(1), 30-37.

Cortical centres underlying auditory temporal processing in humans : A PET study. / Pedersen, Christian Brahe; Mirz, Frank; Ovesen, Therese; Ishizu, Koichi; Johannsen, Peter; Madsen, Stig; Gjedde, Albert.

In: Audiology, Vol. 39, No. 1, 01.2000, p. 30-37.

Research output: Contribution to journalArticle

Pedersen, CB, Mirz, F, Ovesen, T, Ishizu, K, Johannsen, P, Madsen, S & Gjedde, A 2000, 'Cortical centres underlying auditory temporal processing in humans: A PET study', Audiology, vol. 39, no. 1, pp. 30-37.
Pedersen CB, Mirz F, Ovesen T, Ishizu K, Johannsen P, Madsen S et al. Cortical centres underlying auditory temporal processing in humans: A PET study. Audiology. 2000 Jan;39(1):30-37.
Pedersen, Christian Brahe ; Mirz, Frank ; Ovesen, Therese ; Ishizu, Koichi ; Johannsen, Peter ; Madsen, Stig ; Gjedde, Albert. / Cortical centres underlying auditory temporal processing in humans : A PET study. In: Audiology. 2000 ; Vol. 39, No. 1. pp. 30-37.
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