Correlations of cerebrospinal fluid pressure with hemodynamic parameters during thoracoabdominal aortic aneurysm repair

Tam T.T. Huynh, Charles C. Miller, Anthony L. Estrera, Shafi G. Mohamed, Heitham T. Hassoun, Roy Sheinbaum, Eyal E. Porat, Hazim J. Safi

Research output: Contribution to journalArticlepeer-review

Abstract

Central venous pressure (CVP) has long been thought to correlate with cerebrospinal fluid (CSF) pressure during thoracoabdominal aortic aneurysm repair. We examined hemodynamic factors during thoracoabdominal aortic aneurysm surgery to determine their relationship with CSF pressure and aortic cross-clamping. Hemodynamic parameters and CSF pressure were measured in 124 patients at six different stages during repair of descending thoracic or thoracoabdominal aortic aneurysms: skin incision, left lung collapse, pump on, aortic clamp on, aortic clamp off, and pump off. Stepwise multiple regression analysis was used for statistical analysis. CVP was a weak predictor for CSF pressure at the beginning of surgery and when the pump was initiated. At the onset of left lung collapse, cardiac output correlated with CSF pressure. There were no predictors during aortic cross-clamping. Model r 2 values were low, ranging 0.03-0.15. We found no hemodynamic predictors of CSF pressure throughout the period of aortic cross-clamping during descending thoracic or thoracoabdominal aortic aneurysm surgery. Model r 2 values were low, indicating generally poor prediction of CSF pressure.

Original languageEnglish (US)
Pages (from-to)619-624
Number of pages6
JournalAnnals of Vascular Surgery
Volume19
Issue number5
DOIs
StatePublished - Sep 2005

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine

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