Correlations between clusters of protein-DNA binding sites and the binding experimental data allow predicting a structure of regulatory modules

A. A. Nikulova, M. S. Polishchuk, V. G. Tumanian, V. Yu Makeev, A. A. Mironov, A. V. Favorov

Research output: Contribution to journalArticlepeer-review

Abstract

Here we analyzed an option to predict the structure of cis-regulatory modules that consist of binding sites of different proteins (heterogeneous cis-regulatory modules) using mutual positional correlations between protein-DNA binding experimental data and computationally identified clusters of binding sites for each of the proteins.

Original languageEnglish (US)
Pages (from-to)138-139
Number of pages2
JournalBiophysics (Russian Federation)
Volume57
Issue number2
DOIs
StatePublished - Mar 1 2012

Keywords

  • CORE-CLUST
  • CRM
  • ChIP-Seq
  • ChIP-chip
  • GenometriCorr
  • PatternClust
  • binding site cluster
  • cis-regulatory module

ASJC Scopus subject areas

  • Biophysics

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