Correlations between clusters of protein-DNA binding sites and the binding experimental data allow predicting a structure of regulatory modules

A. A. Nikulova; M. S. Polishchuk; V. G. Tumanian; V. Yu Makeev; A. A. Mironov; A. V. Favorov

doi:10.1134/S0006350912020157

Correlations between clusters of protein-DNA binding sites and the binding experimental data allow predicting a structure of regulatory modules

A. A. Nikulova, M. S. Polishchuk, V. G. Tumanian, V. Yu Makeev, A. A. Mironov, A. V. Favorov

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Here we analyzed an option to predict the structure of cis-regulatory modules that consist of binding sites of different proteins (heterogeneous cis-regulatory modules) using mutual positional correlations between protein-DNA binding experimental data and computationally identified clusters of binding sites for each of the proteins.

Original language	English (US)
Pages (from-to)	138-139
Number of pages	2
Journal	Biophysics (Russian Federation)
Volume	57
Issue number	2
DOIs	https://doi.org/10.1134/S0006350912020157
State	Published - Mar 1 2012

Keywords

CORE-CLUST
CRM
ChIP-Seq
ChIP-chip
GenometriCorr
PatternClust
binding site cluster
cis-regulatory module

ASJC Scopus subject areas

Biophysics

Access to Document

10.1134/S0006350912020157

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Correlations between clusters of protein-DNA binding sites and the binding experimental data allow predicting a structure of regulatory modules. / Nikulova, A. A.; Polishchuk, M. S.; Tumanian, V. G.; Makeev, V. Yu; Mironov, A. A.; Favorov, A. V.

In: Biophysics (Russian Federation), Vol. 57, No. 2, 01.03.2012, p. 138-139.

Research output: Contribution to journal › Article › peer-review

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AU - Mironov, A. A.

AU - Favorov, A. V.

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