Correlation of epidermal plasminogen activator activity with disease activity in psoriasis

J. E. FRAKI; G. S. LAZARUs; R. S. GILGOR; PATRICIA MARCHASE; KAY H. SINGER

doi:10.1111/j.1365-2133.1983.tb04577.x

Correlation of epidermal plasminogen activator activity with disease activity in psoriasis

J. E. FRAKI, G. S. LAZARUs, R. S. GILGOR, PATRICIA MARCHASE, KAY H. SINGER

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34 Scopus citations

Abstract

The specific activity of plasminogen activator was increased in clinically involved psoriatic epidermis compared with the uninvolved skin of the same eight patients. Alterations in plasminogen activator activity correlated with disease activity as measured by extent of body surface involved with psoriasis. Levels of plasminogen activator increased in uninvolved epidermis of psoriatic patients during retinoid therapy.

Original language	English (US)
Pages (from-to)	39-44
Number of pages	6
Journal	British Journal of Dermatology
Volume	108
Issue number	1
DOIs	https://doi.org/10.1111/j.1365-2133.1983.tb04577.x
State	Published - Jan 1983
Externally published	Yes

ASJC Scopus subject areas

Dermatology

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10.1111/j.1365-2133.1983.tb04577.x

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title = "Correlation of epidermal plasminogen activator activity with disease activity in psoriasis",

abstract = "The specific activity of plasminogen activator was increased in clinically involved psoriatic epidermis compared with the uninvolved skin of the same eight patients. Alterations in plasminogen activator activity correlated with disease activity as measured by extent of body surface involved with psoriasis. Levels of plasminogen activator increased in uninvolved epidermis of psoriatic patients during retinoid therapy.",

author = "FRAKI, {J. E.} and LAZARUs, {G. S.} and GILGOR, {R. S.} and PATRICIA MARCHASE and SINGER, {KAY H.}",

year = "1983",

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AU - LAZARUs, G. S.

AU - GILGOR, R. S.

AU - MARCHASE, PATRICIA

AU - SINGER, KAY H.

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N2 - The specific activity of plasminogen activator was increased in clinically involved psoriatic epidermis compared with the uninvolved skin of the same eight patients. Alterations in plasminogen activator activity correlated with disease activity as measured by extent of body surface involved with psoriasis. Levels of plasminogen activator increased in uninvolved epidermis of psoriatic patients during retinoid therapy.

AB - The specific activity of plasminogen activator was increased in clinically involved psoriatic epidermis compared with the uninvolved skin of the same eight patients. Alterations in plasminogen activator activity correlated with disease activity as measured by extent of body surface involved with psoriasis. Levels of plasminogen activator increased in uninvolved epidermis of psoriatic patients during retinoid therapy.

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Correlation of epidermal plasminogen activator activity with disease activity in psoriasis

Abstract

ASJC Scopus subject areas

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