Correlaçao entre medidas de proteína C-reativa pelos métodos de nefelometria e turbidimetria em pacientes com angina instável ou infarto agudo do miocárdio sem supradesnível do segmento ST

Translated title of the contribution: Correlation between turbidimetric and nephelometric methods of measuring C-reactive protein in patients with unstable angina or non-ST elevation acute myocardial infarction

Luís Claudio Lemos Correia, José C. Lima, Gary Gerstenblith, Luís P. Magalhães, Agnaluce Moreira, Octávio Barbosa, Juliana Dumet, Luiz Carlos S. Passos, Argemiro D'Oliveira Júnior, José Péricles Esteves

Research output: Contribution to journalArticle

Abstract

Objective - To evaluate the performance of the turbidimetric method of C-reactive protein (CRP) as a measure of low-grade inflammation in patients admitted with non-ST elevation acute coronary syndromes (ACS). Methods - Serum samples obtained at hospital arrival from 68 patients (66±11 years, 40 men), admitted with unstable angina or non-ST elevation acute myocardial infarction were used to measure CRP by the methods of nephelometry and turbidimetry. Results - The medians of C-reactive protein by the turbidimetric and nephelometric methods were 0.5 mg/dL and 0.47 mg/dL, respectively. A strong linear association existed between the 2 methods, according to the regression coefficient (β=0.75; 95% C.I.=0.70-0.80) and correlation coefficient (r=0.96; P<0.001). The mean difference between the nephelometric and turbidimetric CRP was 0.02 ± 0.91 mg/dL, and 100% agreement between the methods in the detection of high CRP was observed. Conclusion - In patients with non-ST elevation ACS, CRP values obtained by turbidimetry show a strong linear association with the method of nephelometry and perfect agreement in the detection of high CRP.

Translated title of the contributionCorrelation between turbidimetric and nephelometric methods of measuring C-reactive protein in patients with unstable angina or non-ST elevation acute myocardial infarction
Original languagePortuguese
Pages (from-to)129-136
Number of pages8
JournalArquivos brasileiros de cardiologia
Volume81
Issue number2
DOIs
StatePublished - Aug 1 2003

Keywords

  • Acute coronary syndromes
  • C-reactive protein
  • Turbidimetric method

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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