TY - JOUR
T1 - Correlates of pericardial adipose tissue volume using multidetector CT scanning in cardiac patients in China
AU - Yang, Ting Ting
AU - Fish, Anne F.
AU - Kong, Wei Min
AU - Gao, Xin
AU - Huang, De Jian
AU - Feng, Ji Tao
AU - Zhu, Jun Ya
AU - Chen, Tao
AU - Lou, Qing Qing
N1 - Publisher Copyright:
© 2017 Elsevier B.V.
PY - 2017/10/1
Y1 - 2017/10/1
N2 - Background Pericardial adipose tissue (PAT) is an emerging cardiovascular risk factor, yet much less is understood about PAT volume in Chinese adults, especially in relation to physical activity. The study explores associations between demographic and clinical variables and PAT volume, using multidetector computed tomography (MDCT) scanning in China. We also examined the relationship between PAT volume and coronary artery disease (CAD). Methods An observational, correlational study design was used. Chinese (n = 163) attended a study visit and underwent MDCT scanning between September 2014 and December 2015. Results Participants were 48.5% male and had a mean age of 60.6 (SD 9.4) years. PAT volume was higher (p = 0.001) in males than in females. PAT volume was correlated with age (r = 0.388, p = 0.001), systolic blood pressure (r = 0.205, p = 0.009), body mass index (r = 0.466, p = 0.001), high-density cholesterol (r = − 0.282, p = 0.001), low-density cholesterol (r = 0.177, p = 0.024), and triglycerides (r = 0.248, p = 0.001). Both moderate intensity physical activity energy consumption (r = − 0.363, p = 0.001) and total physical activity (r = − 0.290, p = 0.001) had inverse relationships with PAT volume. Total sedentary energy consumption was positively related to PAT volume (r = 0.266, p = 0.001). Multiple regression revealed that age, male gender, BMI, LDL-C and total physical activity energy consumption were significant predictors of PAT volume (R2 = 0.465). The relationship between PAT volume and CAD was found to be significant in the adjusted models. Conclusions Age, male gender, BMI, LDL-C and total physical activity energy consumption were significant predictors of PAT volume, and PAT volume itself is a predictor of CAD.
AB - Background Pericardial adipose tissue (PAT) is an emerging cardiovascular risk factor, yet much less is understood about PAT volume in Chinese adults, especially in relation to physical activity. The study explores associations between demographic and clinical variables and PAT volume, using multidetector computed tomography (MDCT) scanning in China. We also examined the relationship between PAT volume and coronary artery disease (CAD). Methods An observational, correlational study design was used. Chinese (n = 163) attended a study visit and underwent MDCT scanning between September 2014 and December 2015. Results Participants were 48.5% male and had a mean age of 60.6 (SD 9.4) years. PAT volume was higher (p = 0.001) in males than in females. PAT volume was correlated with age (r = 0.388, p = 0.001), systolic blood pressure (r = 0.205, p = 0.009), body mass index (r = 0.466, p = 0.001), high-density cholesterol (r = − 0.282, p = 0.001), low-density cholesterol (r = 0.177, p = 0.024), and triglycerides (r = 0.248, p = 0.001). Both moderate intensity physical activity energy consumption (r = − 0.363, p = 0.001) and total physical activity (r = − 0.290, p = 0.001) had inverse relationships with PAT volume. Total sedentary energy consumption was positively related to PAT volume (r = 0.266, p = 0.001). Multiple regression revealed that age, male gender, BMI, LDL-C and total physical activity energy consumption were significant predictors of PAT volume (R2 = 0.465). The relationship between PAT volume and CAD was found to be significant in the adjusted models. Conclusions Age, male gender, BMI, LDL-C and total physical activity energy consumption were significant predictors of PAT volume, and PAT volume itself is a predictor of CAD.
KW - Cardiac imaging
KW - Pericardial adipose tissue
KW - Physical activity
KW - Sedentary
UR - http://www.scopus.com/inward/record.url?scp=85021764516&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85021764516&partnerID=8YFLogxK
U2 - 10.1016/j.ijcard.2017.06.114
DO - 10.1016/j.ijcard.2017.06.114
M3 - Article
C2 - 28684043
AN - SCOPUS:85021764516
SN - 0167-5273
VL - 244
SP - 285
EP - 289
JO - International Journal of Cardiology
JF - International Journal of Cardiology
ER -